Results 271 to 280 of about 89,492 (311)
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Adhesion of PLGA or Eudragit®/PLGA nanoparticles to Staphylococcus and Pseudomonas
International Journal of Pharmaceutics, 2008The aim of present study was to examine whether cationic Eudragit containing poly(lactide-co-glycolide) (PLGA) nanoparticles can adhere to Pseudomonas aeruginosa and Staphylococcus aureus. In order to prepare fluorescent nanoparticles, fluorescein was covalently coupled to PLGA.
Dillen, Kathleen +7 more
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Journal of Polymer Science Part A: Polymer Chemistry, 2018
ABSTRACTThermoresponsive, biodegradable polymeric hydrogel networks are used widely in medicinal applications. Poly(d,l‐lactic acid‐co‐glycolic acid)‐b‐poly(ethylene glycol)‐b‐poly(d,l‐lactic acid‐co‐glycolic acid) (PLGA‐PEG‐PLGA) triblock copolymers exhibit a sol–gel transition upon heating.
Noam Y. Steinman +6 more
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ABSTRACTThermoresponsive, biodegradable polymeric hydrogel networks are used widely in medicinal applications. Poly(d,l‐lactic acid‐co‐glycolic acid)‐b‐poly(ethylene glycol)‐b‐poly(d,l‐lactic acid‐co‐glycolic acid) (PLGA‐PEG‐PLGA) triblock copolymers exhibit a sol–gel transition upon heating.
Noam Y. Steinman +6 more
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Release of rifampicin from chitosan, PLGA and chitosan-coated PLGA microparticles
Colloids and Surfaces B: Biointerfaces, 2008Recently three groups of rifampicin (RIF)-loaded microparticles (MPs), consisting of chitosan (CHT), PLGA and PLGA/CHT mixtures, were assessed in terms of RIF-loading and retention during nebulisation. The CHT-coated PLGA MPs were found to exhibit high RIF-loading ability together with nebulisation ability, stability, and mucoadhesive properties.
MANCA, MARIA LETIZIA +4 more
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Synthesis and characterization of elastic PLGA/PCL/PLGA tri-block copolymers
Journal of Biomaterials Science, Polymer Edition, 2002Various ABA-type tri-block copolymers composed of poly(L-lactide) (PLA) or poly (lactide-co-glycolide) (PLGA) as the side A block and poly(epsilon-caprolactone) (PCL) as the middle B block were synthesized to produce rapidly degrading elastic matrices useful for tissue engineering scaffolds.
Choi, SH, Park, TG
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Biodegradable Triblock Copolymer of PLGA-PEG-PLGA Enhances Gene Transfection Efficiency
Pharmaceutical Research, 2004A tri-block copolymer of PLGA-PEG-PLGA was used as an excipient to enhance the gene transfection efficiency of various cationic polymeric carriers.Luciferase plasmid DNA was complexed with polyethylenimine for gene transfection. Various concentrations of PLGA-PEG-PLGA copolymer up to 0.5% were added in the transfection medium to explore whether the ...
Jeong, JH, Kim, SW, Park, TG
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2022
Diese Arbeit handelt von der Charakterisierung der Größe sowie Größenverteilung und freisetzungsspezifischer Eigenschaften von Testosteronbeladenen Mikropartikeln, welche mit PLGA unterschiedlicher Molekulargewichte mittels Solvent Evaporation Methode hergestellt wurden. Weiters wurde die Möglichkeit einer Oberflächenoptimierung von PLGA-Mikropartikel,
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Diese Arbeit handelt von der Charakterisierung der Größe sowie Größenverteilung und freisetzungsspezifischer Eigenschaften von Testosteronbeladenen Mikropartikeln, welche mit PLGA unterschiedlicher Molekulargewichte mittels Solvent Evaporation Methode hergestellt wurden. Weiters wurde die Möglichkeit einer Oberflächenoptimierung von PLGA-Mikropartikel,
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PLGA–PEG–PLGA hydrogel for ocular drug delivery of dexamethasone acetate
Drug Development and Industrial Pharmacy, 2010This study aims to investigate the suitability of thermosensitive triblock polymer poly-(DL-lactic acid-co-glycolic acid) (PLGA)-polyethylene glycol (PEG)-PLGA as a matrix material for ocular delivery of dexamethasone acetate (DXA).The copolymer was synthesized and evaluated for its thermosensitive and gelation properties.
Yuan, Gao +3 more
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Biomacromolecules
Hydrogels are promising materials for biomedical applications, particularly in drug delivery and tissue engineering. This study highlights thermoresponsive hydrogels, specifically poly(lactic-co-glycolic acid) (PLGA)-poly(ethylene glycol) (PEG)-PLGA triblock copolymers, and introduces a feed rate-controlled polymerization (FRCP) method. By utilizing an
SeongHoon Jo +8 more
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Hydrogels are promising materials for biomedical applications, particularly in drug delivery and tissue engineering. This study highlights thermoresponsive hydrogels, specifically poly(lactic-co-glycolic acid) (PLGA)-poly(ethylene glycol) (PEG)-PLGA triblock copolymers, and introduces a feed rate-controlled polymerization (FRCP) method. By utilizing an
SeongHoon Jo +8 more
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Rheological properties of PLGA‐PEG‐PLGA copolymers for ophthalmic injection
Journal of Applied Polymer Science, 2011AbstractPolymer rheological property is one of intrinsic properties for the design and preparation of intravitreal injection systems. Rheological behaviors of thermosensitive poly(lactic acid‐co‐glycolic acid)‐poly(ethylene glycol)‐poly(lactic acid‐co‐glycolic acid) (PLGA‐PEG‐PLGA) triblock copolymers were investigated in this article.
Bochu Wang +3 more
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Functionalization Conditions of PLGA‐PEG‐PLGA Copolymer with Itaconic Anhydride
Macromolecular Symposia, 2010AbstractSummary: Biodegradable thermosensitive triblock copolymers based on poly(ethylene glycol) and poly(lactic‐co‐glycolic acid) (PLGA‐PEG‐PLGA) prepared via ring opening polymerization were modified by itaconic anhydride (ITA), which gives copolymer both reactive double bonds and functional carboxylic acid groups essential for the reaction with ...
Lenka Michlovská +5 more
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