Results 281 to 290 of about 89,492 (311)
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Progesterone PLGA/mPEG-PLGA Hybrid Nanoparticle Sustained-Release System by Intramuscular Injection
Pharmaceutical Research, 2018To prepare sustained-release PLGA/mPEG-PLGA hybrid nanoparticles of progesterone (PRG), and evaluate the descending required administration dosage in vivo.PRG hybrid nanoparticles (PRG H-NPs) based on PLGA/mPEG-PLGA were compared with PRG nanoparticles (PRG-NPs) of pure PLGA as the matrix and PRG-oil solutions.
Bin, Xie +7 more
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PLGA Nanoparticles and Transdermal Delivery
Recent Patents on Nanotechnology, 2023openaire +2 more sources
Functionalizing PLGA and PLGA Derivatives for Drug Delivery and Tissue Regeneration Applications
Advanced Healthcare Materials, 2017AbstractPoly(lactic‐co‐glycolic) acid (PLGA) is one of the most versatile biomedical polymers, already approved by regulatory authorities to be used in human research and clinics. Due to its valuable characteristics, PLGA can be tailored to acquire desirable features for control bioactive payload or scaffold matrix.
Cláudia Martins +3 more
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A thermo-sensitive PLGA-PEG-PLGA hydrogel for sustained release of docetaxel
Journal of Drug Targeting, 2010The aim of this study was to investigate the suitability of poly-(d,l-lactic acid-co-glycolic acid) (PLGA)-polyethylene glycol (PEG)-PLGA triblock copolymer as a matrix material for a sustained-release system for docetaxel (DTX). The copolymers were synthesized by ring-opening polymerization reaction and characterized by (1)H-NMR and gel permeation ...
Yuan, Gao +6 more
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Biomacromolecules, 2011
This paper reports the influence of sequence structures of block copolymers composed of poly(lactic acid-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) on their thermogelling aqueous behaviors. A series of thermogelling PLGA-PEG-PLGA triblock copolymers with similar chemical compositions and block lengths but different sequences of D,L ...
Lin, Yu, Zheng, Zhang, Jiandong, Ding
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This paper reports the influence of sequence structures of block copolymers composed of poly(lactic acid-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) on their thermogelling aqueous behaviors. A series of thermogelling PLGA-PEG-PLGA triblock copolymers with similar chemical compositions and block lengths but different sequences of D,L ...
Lin, Yu, Zheng, Zhang, Jiandong, Ding
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ACS Biomaterials Science & Engineering, 2018
This study is aimed at investigation of the osteochondral regeneration potential of bilayered PLGA/PLGA-HAp composite scaffolds with one layer made of biodegradable polymer poly(d,l-lactide-co-glycolide) (PLGA) and another layer made of PLGA polymeric matrix coated by bioactive ceramics hydroxyapatite (HAp).
Xiangyu Liang +8 more
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This study is aimed at investigation of the osteochondral regeneration potential of bilayered PLGA/PLGA-HAp composite scaffolds with one layer made of biodegradable polymer poly(d,l-lactide-co-glycolide) (PLGA) and another layer made of PLGA polymeric matrix coated by bioactive ceramics hydroxyapatite (HAp).
Xiangyu Liang +8 more
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PKPD of PLGA-PEG-PLGA Copolymeric Micelles
2022Shirleen Miriam Marques, Lalit Kumar
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2014
Nowadays, the potential use of micro- and nanoparticles for drug delivery purposes is intensively investigated. Different molecules can be loaded into particles by selected techniques and even the surface of the drug carriers can be structurally modified. This allows for prolonged residence time of micro- and nanoparticles in the circulation increasing
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Nowadays, the potential use of micro- and nanoparticles for drug delivery purposes is intensively investigated. Different molecules can be loaded into particles by selected techniques and even the surface of the drug carriers can be structurally modified. This allows for prolonged residence time of micro- and nanoparticles in the circulation increasing
openaire +1 more source
Physicochemical Characterization of Photopolymerizable Plga Blends
2007Photopolymerizable systems have been proposed as good candidates for drug delivery 1, 2, 3, 4, 5, 6 and tissue engineering 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18 for their ability to be produced in vivo via minimally invasive surgery upon light or UV exposure. However, these systems might show poor light penetration or light scattering through the
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