Results 181 to 190 of about 282,554 (281)

Laparoscopic endoscopic preaponeurotic repair (REPA) for rectus diastasis with concomitant ventral and umbilical hernias: a case report and literature review. [PDF]

J Surg Case Rep
Llerena Freire LF, Llerena Meza FE, Aguirre Vásconez LDC.   +2 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A modified LIFT approach of offsetting sphincter muscle plication aimed at decreasing recurrence rates: a single-center retrospective review. [PDF]

Tech Coloproctol
Troester A, Frebault J, Von Der Marwitz E, Arsoniadis E, Goldberg SM, Goffredo P, Jahansouz C.   +6 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Subcutaneous versus retromuscular approach for the minimally invasive surgical treatment of rectus diastasis with concomitant ventral hernia: systematic review and meta-analysis of current techniques. [PDF]

Hernia
Castagneto-Gissey L, Russo MF, Palumbo P, Casella-Mariolo J, D'Andrea V, Bellini MI, Illuminati G, Casella G.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

An extremely rare tetralogy of Fallot with absent pulmonary valve and unilateral absence of the pulmonary artery: a rare report of De Bucket Syndrome. [PDF]

Egypt Heart J
Jalali A, Mahdavi M, Ganjifard M, Nabavi SS, Bakhtiari M, Ansari Aval Z, Hosseini Zargaz SE.   +6 more
europepmc   +1 more source

THORACOMEDIASTINAL PLICATION

The Journal of Thoracic and Cardiovascular Surgery, 1961
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

"Pinch-and-Tuck" Arthroscopic Technique for Capsular Laxity in Posterior Shoulder Instability. [PDF]

Arthrosc Tech
Sheth CD, Field LD.
europepmc   +1 more source