Results 71 to 80 of about 22,535 (282)

Prognostic impact of the lymph node metastatic ratio on 5-year survival of patients with rectal cancer not submitted to preoperative chemoradiation

Journal of Coloproctology, 2011
Lymph node metastases are a major prognostic factor in colorectal cancer. Inadequate lymph node resection is related to shorter survival. The lymph nodes ratio (LNR) has been used as a prognostic factor in patients with colon cancer.
Alfredo Luiz Jacomo, Carlos Augusto Real Martinez, Marcia Milena Pivatto Serra, Flávia Emi Akamatsu, José Aires Pereira, Mauro Figueiredo Carvalho de Andrade, Nelson Fontana Margarido   +6 more
doaj   +1 more source

NToxSEM: Enhancing prediction of neurotoxic peptides and neurotoxins using a stacked ensemble-based multimodal framework. [PDF]

Protein Sci
Abstract The safety assessment of therapeutic proteins and genetically modified (GM) organisms relies heavily on the rapid and accurate prediction of peptides, and proteins that exhibit neurotoxic activity. Since experimental methods are time‐consuming and costly, they are not technically suitable for the cost‐effective characterization of neurotoxic ...
Shoombuatong W, Schaduangrat N, Mahmud SMH, Ahmed S.   +3 more
europepmc   +2 more sources

Practitioner requirements for integrated Knowledge-Based Engineering in Product Lifecycle Management.

, 2008
The effective management of knowledge as capital is considered essential to the success of engineering product/service systems. As Knowledge Management (KM) and Product Lifecycle Management (PLM) practice gain industrial adoption, the question of ...
Bermell-Garcia, Pablo, Fan, Ip-Shing
core   +1 more source

A second species of non‐crocodyliform crocodylomorph from the Late Triassic fissure deposits of southwestern UK: Implications for locomotory ecological diversity in Saltoposuchidae

The Anatomical Record, EarlyView.
Abstract The Late Triassic–Early Jurassic fissures of the Bristol Channel area (southwest England and south Wales) are renowned for their diverse vertebrate faunas. These assemblages have yielded an array of predominantly small‐bodied forms that are crucial to our understanding of the early evolution of several major tetrapod clades.
Ewan H. Bodenham, Stephan N. F. Spiekman, Susannah C. R. Maidment, Paul Upchurch, Philip D. Mannion   +4 more
wiley   +1 more source

Evaluation of the objective Posturo-Locomotor-Manual (PLM) method in patients with Parkinsonian syndromes

Frontiers in Neurology, 2013
Objective methods for quantifying patients' movement capacity would be valuable for evaluating progression and interventions in neurodegenerative diseases.
Theresa eZackrisson, Filip eBergquist, Filip eBergquist, Björn eHolmberg, Björn eHolmberg, Bo eJohnels, Thorleif eThorlin, Thorleif eThorlin   +7 more
doaj   +1 more source

How Do Carbon Emissions Affect the Performance of Listed Latin American Firms? The Moderating Effect of Financial Slack

Business Strategy and the Environment, EarlyView.
ABSTRACT This study analyses the association between carbon emissions and financial performance in Latin American firms. The scientific literature on this topic is limited, with little evidence available in this geographical region. This study aims to address this research gap by testing hypotheses focused on analysing how Scope 1, 2 and 3 carbon ...
Ana Isabel Mendieta‐Callirgos, Maria Carmen Pérez‐López, Ismael Muñoz‐Pérez, Germán López‐Pérez   +3 more
wiley   +1 more source

Sharing and Managing Sustainability Information and Data in Collaborative Ecosystems—Insights From Testing a Novel Assessment Method With the Automotive Industry

Business Strategy and the Environment, EarlyView.
ABSTRACT The manufacturing industry is under pressure from upcoming legislation and societal expectations to design sustainable solutions, requiring improved intraorganizational and interorganizational collaboration to ensure sustainability is integrated throughout the product's lifecycle.
Adam Mallalieu, Ola Isaksson, Sophie Isaksson Hallstedt, Matilda Sandgren Watz, Giliam Dokter, Lars Almefelt   +5 more
wiley   +1 more source

Identification of Critical Building Blocks in PLM System Implementation in the Automotive Supply Chain [PDF]

, 2017
In today’s industrialised world, manufacturers must adapt and evolve their Product Development (PD) processes through the adoption of bespoke ICT tools.
Zammit, J.P., Evans, R.D., Gao, J.X.
core   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Current state of sustainability representation product lifecycle management systems and future Perspectives: A comparative evaluation

Cleaner Logistics and Supply Chain
This paper presents a comprehensive evaluation of Product Lifecycle Management (PLM) systems and their integration with sustainability practices. With increasing pressure on industries to align with global sustainability standards, the role of PLM ...
Anders M.S.Ø. Jakobsen, Torben Tambo
doaj   +1 more source