Results 161 to 170 of about 4,591 (253)

Expanding the Spectrum of Canine Diffuse Large B‐Cell Lymphoma Genetic Aberrations Through Whole Genome Sequencing Analysis

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is one of the most prevalent haematological malignancies in both humans and dogs, characterised in both species by significant clinical heterogeneity and limited prognostic predictability. With the introduction of next‐generation sequencing (NGS) technologies in veterinary medicine over the past decade ...
Antonella Fanelli, Eugenio Mazzone, Diana Giannuzzi, Laura Marconato, Luca Aresu   +4 more
wiley   +1 more source

Physiology and Robustness of Yeasts Exposed to Dynamic pH and Glucose Environments

Biotechnology and Bioengineering, Volume 122, Issue 7, Page 1656-1668, July 2025.
The authors investigated how three Saccharomyces cerevisiae strains respond to dynamic substrate and pH oscillations using dynamic microfluidic single‐cell cultivation (dMSCC) and intracellular biosensors. By combining performance and robustness analysis of selected intracellular parameters, growth and morphological analysis, the authors identified ...
Luca Torello Pianale, Luisa Blöbaum, Alexander Grünberger, Lisbeth Olsson   +3 more
wiley   +1 more source

Chemical Switching: A Concept Inspired by Strategies from Biocatalysis and Organocatalysis

ChemBioChem, Volume 26, Issue 11, June 3, 2025.
Chemical Switching is introduced as a novel technology that exploits the promiscuity of enzymatic transformations by applying small molecule organocatalytic switches (ORCAs) or gain‐of‐function protein variants. The modulation of underlying chemical principles thereby amplifies low‐rate or installs otherwise absent enzymatic activities to dominate ...
Torkild Visnes, Kaixin Zhou, Aurino M. Kemas, Dominic Campopiano, Volker M. Lauschke, Maurice Michel   +5 more
wiley   +1 more source

Haploid induction in sweet potato by activating the AP2/ERF family transcription factor IbBBM

Plant Biotechnology Journal, EarlyView.
Wenpeng Song, Yixuan Zhu, Junyao Zheng, Hong Zhai, Shaozhen He, Huan Zhang, Ning Zhao, Qingchang Liu, Shaopei Gao   +8 more
wiley   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, Volume 19, Issue 6, Page 1751-1774, June 2025.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Resistance of banana cultivars against Fusarium oxysporum f. sp. cubense in southern Ethiopia

Agrosystems, Geosciences &Environment, Volume 8, Issue 2, June 2025.
Abstract Fusarium wilt caused by the fungal pathogen Fusarium oxysporum f. sp. cubense (Foc) is one of the major threats challenging the banana industry in tropics including Ethiopia. Foc infects the xylem, induces wilt, and kills banana plants. Hence, it affects the production and productivity of both commercial and local banana cultivars. In southern
Biruk Kedir, Chemeda Fininsa, Zelalem Bekeko, Abdi Mohammed   +3 more
wiley   +1 more source

Comparison of the morphological and physiological characteristics of diploid and tetraploid Luculia pinceana Hook. [PDF]

BMC Plant Biol
Wang L, Li Y, Li H, Li S, Song J, Guan W.   +5 more
europepmc   +1 more source

Advancing wheat breeding in Ethiopia: Challenges and opportunities in breeding for nutrient use efficiency: A review

Agrosystems, Geosciences &Environment, Volume 8, Issue 2, June 2025.
Abstract Wheat plays a critical role in Ethiopia's food security, nutrition, and economic development. Despite increased production and expansion into diverse agro‐ecological zones, productivity remains constrained by soil nutrient depletion, inefficient fertilizer use, and low adoption of best agronomic practices.
Tesfaye Geleta Aga
wiley   +1 more source

Integration of Optical Genome Mapping in the Cytogenomic and Molecular Work‐Up of Hematological Malignancies: Expert Recommendations From the International Consortium for Optical Genome Mapping

American Journal of Hematology, Volume 100, Issue 6, Page 1029-1048, June 2025.
ABSTRACT The latest updates to the classification of hematolymphoid malignancies using the World Health Organization (WHO, 5th ed.) and ICC (International Consensus Classification) criteria highlight the critical need for comprehensive and precise cytogenomic data for diagnosis, prognostication, and treatment.
Rashmi Kanagal‐Shamanna, Anna Puiggros, Isabel Granada, Gordana Raca, Katrina Rack, Mar Mallo, Barbara Dewaele, Adam C. Smith, Yassmine Akkari, Brynn Levy, Robert P. Hasserjian, Adela Cisneros, Marta Salido, Guillermo Garcia‐Manero, Hui Yang, M. Anwar Iqbal, Ravindra Kolhe, Francesc Solé, Blanca Espinet   +18 more
wiley   +1 more source

Polyploidy drives changes in tissue allocation modifying whole-plant water relations. [PDF]

Plant Physiol
López-Jurado J, Bourbia I, Brodribb TJ.
europepmc   +1 more source