Results 241 to 250 of about 37,805 (321)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, Volume 599, Issue 21, Page 3124-3149, November 2025.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Clinical application of single‐cell RNA sequencing in disease and therapy

open access: yesClinical and Translational Medicine, Volume 15, Issue 11, November 2025.
This review provides a comprehensive overview of the application of scRNA‐seq in revisiting the somatic cell evolutions in human diseases, as well as in biomarker discovery and drug development. Abstract Background The emergence of single‐cell RNA sequencing (scRNA‐seq) technology has revolutionized our capacity to study cell functions in complex ...
Aisha Shigna Nadukkandy   +3 more
wiley   +1 more source

Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, Volume 254, Issue 11, Page 1203-1220, November 2025.
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak   +4 more
wiley   +1 more source

Tracing Scots Pine Expansion in Europe Using Patterns of Rare Alleles

open access: yesEcology and Evolution, Volume 15, Issue 11, November 2025.
Strong and early demographic expansions from the Carpathian region shapes the current patterns of genetic diversity of Pinus sylvestris across Europe. ABSTRACT Past climatic oscillations have likely played a key role in the evolution of all tree species in Europe, by causing alternating phases of range expansions and population declines.
Chedly Kastally   +6 more
wiley   +1 more source

Relationship between DNA ploidy and Survival Time in Small Cell Lung Cancer [PDF]

open access: bronze, 1995
Joong Ho Song   +3 more
openalex   +1 more source

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