Results 161 to 170 of about 829,101 (387)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

O emprego de computadores na história

open access: yesRevista de História, 1973
Na presente Comunicação, serão focalizados exemplos do emprego de computação eletrônica em Projetos de pesquisa histórica, desenvolvidos no Departamento de História da Universidade Federal do Paraná, e que se vêm utilizando os serviços do computador IBM ...
Altiva Pilatti Balhana   +1 more
doaj  

The general functional relationship language system [PDF]

open access: yes
Symbolic language for expressing functional relationships of space vehicle ...

core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

A study of digital holographic filter generation [PDF]

open access: yes
Problems associated with digital computer generation of holograms are discussed along with a criteria for producing optimum digital holograms. This criteria revolves around amplitude resolution and spatial frequency limitations induced by the computer ...
Calhoun, M., Ingels, F.
core   +1 more source

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