Results 171 to 180 of about 829,101 (387)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

A research to reduce interior noise in general aviation airplanes. General aviation interior noise study [PDF]

open access: yes
The construction, calibration, and properties of a facility for measuring sound transmission through aircraft type panels are described along with the theoretical and empirical methods used.
Muirhead, V. U.   +3 more
core   +1 more source

A plotter sequencing system [PDF]

open access: yesThe Computer Journal, 1979
Timo Leipälä, Olli Nevalainen
openaire   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Increased expression of TMED2 is an unfavorable prognostic factor in patients with breast cancer

open access: yesCancer Management and Research, 2019
Xia Lin,1 Jian Liu,2 Shu Fang Hu,2 Xun Hu11Cancer Institute (a Key Laboratory for Cancer Prevention & Intervention, China National Ministry of Education), the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People&rsquo ...
Lin X, Liu J, Hu SF, Hu X
doaj  

A preliminary systems study of interface equipment for digitally programmed flight simulators [PDF]

open access: yes
Design study of digitally programmed supersonic transport flight ...
Du Lac, K. B., Johnson, E. L.
core   +1 more source

Picasso : CNC plotter

open access: yes, 2018
In today’s society, CNC machines are used for various purposes.In this project, a CNC plotter is created to analyzehow the performance of the plotter differs when using twodifferent motors: a DC motor controlled by a potentiometerin the horizontal direction and a stepper motor in thevertical direction.
PERSSON, LINUS, ZIVANOVIC, NATALIJA
openaire   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

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