Results 141 to 150 of about 3,488 (265)

Dealing With Inbuilt Age: A Bayesian Approach to Radiocarbon Dating of Rice, Bamboo and Charcoal From Non Ban Jak, Thailand

open access: yesArchaeometry, EarlyView.
ABSTRACT New radiocarbon determinations from rice grains and bamboo have been obtained from Non Ban Jak, Northeast Thailand. These, along with charcoal, date a late Iron Age building sequence. The results come from short‐lived species and charcoal with potential inbuilt age. We built a series of Bayesian models to obtain a reliable chronology.
C. F. W. Higham, T. F. G. Higham
wiley   +1 more source

The Early Upper Palaeolithic open‐air site of Friedrichsdorf‐Seulberg, Germany, in the context of the northern central European Aurignacian

open access: yesBoreas, EarlyView.
Our knowledge of the Early Upper Palaeolithic occupation in northern central Europe is very limited, and recent research at the open‐air site of Friedrichsdorf‐Seulberg in Hesse, Germany, provides important new information on the Aurignacian. The site is rather small (26.5 m2) and spatial analysis identified a central hearth with two associated ...
Tilman Böckenförde   +5 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown   +2 more
wiley   +1 more source

Soil organic carbon stocks after ten years of reduced tillage, compost and mulch application in temperate organic agriculture. [PDF]

open access: yesSci Rep
Niether W   +8 more
europepmc   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu   +5 more
wiley   +1 more source

An experimental approach to assess the combined effects of multiple stressors on a large vertebrate species

open access: yesConservation Biology, EarlyView.
Abstract The design of experiments to investigate the combined effects of multiple stressors requires exposing target organisms to multiple combinations of stressor doses. Concurrent manipulation of stressors is often infeasible with wildlife, but long‐lasting health effects allow individual health to be used as an integrator of prior stressor exposure.
Enrico Pirotta   +24 more
wiley   +1 more source

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