Results 81 to 90 of about 32,817 (185)

Factors Associated With Omalizumab Response in Chronic Spontaneous Urticaria: Are There Age‐Related Differences?

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study aimed to explore clinical and laboratory markers of omalizumab response in paediatric and adult chronic spontaneous urticaria (CSU) patients. Methods The study included 32 children and 67 adults with CSU receiving omalizumab, and 29 paediatric and 30 adult healthy controls; associations with treatment response were evaluated ...
Güler Yıldırım Nalbant, Raif Coşkun, Nilay Çalışkan, Merve Karaca Şahin, Aslı Berivan Topçak, Muhammed Fatih Erbay, Çağla Öztürk Turan, Hilal Güngör, Hamit Boloğur, Hasan Tunç Şarman, Şule Papağan, Ömer Yılmaz Ulutaş, Şefika İlknur Kökçü Karadağ, Özlem Terzi, Deniz Özçeker   +14 more
wiley   +1 more source

ALBI‐6—A Novel Prognostic Score Combining ALBI and Interleukin‐6 in Patients With HCC Treated With Atezolizumab and Bevacizumab

Alimentary Pharmacology &Therapeutics, EarlyView.
ALBI‐6, a novel score combining albumin–bilirubin grade and interleukin‐6, showed improved prognostic discrimination compared with established scores in patients with advanced hepatocellular carcinoma treated with atezolizumab plus bevacizumab, supporting its potential use for risk stratification in this setting.
Paula Bark, Lucas Wiesmann, Simon Johannes Gairing, Kateryna Shmanko, Lukas Müller, Maximilian Moos, Fabian Stöhr, Dirk Graafen, Tilman Emrich, Felix Hahn, Daniel Pinto dos Santos, Bernhard Scheiner, Victoria Berit Berger, Matthias Pinter, Valentina Zarka, Florian P. Reiter, Andreas Geier, Najib Ben Khaled, Alexander Philipp, Christoph Springfeld, Aurelie Tomczak, Michael T. Dill, Constantin Scholz, Jens Mittler, Hauke Lang, Beate Katharina Straub, Roman Kloeckner, Tobias Bäuerle, Christian Markus Lange, Arndt Weinmann, Peter Robert Galle, Friedrich Foerster   +31 more
wiley   +1 more source

Analysis of laboratory parameters in patients with pemphigus vulgaris complicated with infections

Pifu-xingbing zhenliaoxue zazhi
[Objective] To analyze the association between laboratory parameters and pemphigus vulgaris (PV) complicated with infections, aiding in assessment of disease progression and prevention of infection.
ZHAO Shiqi, MIAO Qing, ZHANG Xiaohan
doaj   +1 more source

Ocular and cutaneous infection due to Curvularia pseudobrachyspora in an immunosuppressed dog: Case report and in vitro antimycotic susceptibilities

Australian Veterinary Journal, EarlyView.
A 3‐year‐old male Border Collie diagnosed with immune‐mediated dermatopathy, managed with tapering prednisolone and cyclosporine, developed rapidly progressive ocular signs and additional cutaneous lesions. Histopathology, mycological culture, polymerase chain reaction and sequencing confirmed intraocular and cutaneous infection due to Curvularia ...
T Brasil‐Ervedosa, R Clark, J Granados‐Soler, C Palmieri, V Gonzalez‐Astudillo   +4 more
wiley   +1 more source

Lung Cancer Brain Metastasis: Brain Microenvironmental Adaptation, Therapeutic Resistance and Translational Strategies

Cancer Science, EarlyView.
Lung cancer brain metastasis is shaped by dynamic crosstalk among tumor cells, the blood–brain barrier, glial and immune cells, neurons, and metabolic niches. This review integrates these mechanisms with therapeutic resistance, translational models, CNS delivery, and multidisciplinary treatment strategies.
Jun Yang, Junyi Xiong, Li Ying, Yanyang Zeng, Ziqiang Ouyang, Mei Liu, Meihua Li   +6 more
wiley   +1 more source

Can the Neutrophil/Lymphocyte*Platelet Ratio Predict Acute Appendicitis? An Analytical Study

Namık Kemal Tıp Dergisi
Aim: Our primary aim is to determine whether the neutrophil/lymphocyte*platelet ratio (NLPR) has the ability to predict acute appendicitis. Our secondary aim is to show whether the NLPR is effective in differentiating complicated and non-complicated ...
Abuzer ÖZKAN, Serdar ÖZDEMİR, Hatice Şeyma AKÇA, Muhammed Tahir AKÇA   +3 more
doaj   +1 more source

Diagnostic Performance of cfDNA‐Based Liquid Biopsy for Hepatocellular Carcinoma: A Systematic Review and Meta‐Analysis

Cancer Science, EarlyView.
This meta‐analysis demonstrates high diagnostic accuracy of cfDNA‐based liquid biopsy for HCC, with stage‐ and assay‐dependent performance and substantial inter‐study heterogeneity. ABSTRACT Conventional surveillance tools for hepatocellular carcinoma (HCC) have limited sensitivity.
Jiwei Liu, Yangyu Zhang, Shuo Yang, Yanhua Wu, Jing Jiang   +4 more
wiley   +1 more source

Diagnostic Options in Graves' or Non‐Graves' Thyrotoxicosis: A Review for Clinical Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Distinguishing Graves' disease (GD) from the other causes of thyrotoxicosis is essential for appropriate management. The clinical phenotype of GD has evolved over time and is currently more heterogenous and milder than in the past. Consequently, the differential diagnosis of thyrotoxicosis is often challenging.
Lorenzo Scappaticcio, Pierpaolo Trimboli, Paola Caruso, Chiara Porcellini, Daniela Forestiere, Maria Ida Maiorino, Katherine Esposito, Giuseppe Bellastella   +7 more
wiley   +1 more source

Polygenic Risk Scores for Islet Autoantibody Positive Early‐Stage Type 1 Diabetes Pre‐Screening

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To develop a sex‐aligned polygenic risk score (PRS) for early‐stage type 1 diabetes (T1D) in children without a first‐degree family history of T1D. Materials and Methods Global Single Nucleotide Polymorphism (SNP) Array was performed in 16 335 individuals without a first‐degree family history of T1D, including 13 956 newborns from the ...
Jose Zapardiel‐Gonzalo, Christiane Winkler, Florian Haupt, Manja Jolink, Alexandra Käßl, Konstantinos Hatzikotoulas, Anette‐G. Ziegler, Ezio Bonifacio   +7 more
wiley   +1 more source

Longitudinal changes in readily available inflammatory markers before and after switching to integrase inhibitor‐based antiretroviral therapy in Virologically suppressed people living with HIV: A Nationwide real‐world cohort study

HIV Medicine, EarlyView.
Abstract Background Persistent immune activation and systemic inflammation remain key features of chronic HIV infection despite sustained virological suppression under antiretroviral therapy (ART), contributing to excess non‐AIDS morbidity and mortality.
Stelios Assimakopoulos, Achilleas Stamoulopoulos, Mina Psichogiou, Varvara Vasalou, Vasileios Papastamopoulos, Antonis Papadopoulos, Georgios Adamis, Maria Chini, Simeon Metallidis, Georgios Loizos, Lydia Leonidou, Helen Sambatakou, Markos Marangos, Diamantis Kofteridis, Giota Touloumi, on behalf of AMACS, G. Adamis, M. Chini, G. Chrysos, M. Marangos, O. Katsarou, D. Kofteridis, S. Metallidis, P. Panagopoulos, N. Pantazis, A. Papadopoulos, V. Paprizos, V. Papastamopoulos, M. Psichogiou, H. Sambatakou, NV. Sipsas, G. Touloumi, G. Touloumi, N. Pantazis, C. Thomadakis, A Stamoulopoulos, A Papadopoulos, A Antoniadou, C Protopapas, D Kavatha, G Chrysos, T Nitsotolis, M Psichogiou, E Mastrogianni, G Adamis, M Astriti, MN Marangos, L Leonidou, O Katsarou, A Kouramba, NV Sipsas, A Kontos, D Basoulis, M Chini, G Tsekes, N Mangafas, S Metallidis, O Tsachouridou, Τ Chrysanthidis, V Paparizos, V Vasalou, S Kourkounti, H Sambatakou, V Papastamopoulos, G Lourida, P Panagopoulos, V Petrakis, D Kofteridis, K Alexakis, V Malikidis, H Gogos, M Psichogiou   +71 more
wiley   +1 more source