Results 211 to 218 of about 10,308 (218)

Disentangling Organ‐Specific Roles of Farnesoid X Receptor in Bile Acid and Glucolipid Metabolism

open access: yesLiver International, Volume 45, Issue 4, April 2025.
ABSTRACT Background and Aims The farnesoid X receptor (FXR) is an attractive pharmaceutical target for metabolic dysfunction‐associated steatotic liver disease (MASLD). However, its tissue‐specific roles in energy metabolism remain controversial, hindering the development of effective therapies. To address this, new approaches are required.
Tingting Li   +12 more
wiley   +1 more source

Human adenovirus serotype 5 infection dysregulates cysteine, purine, and unsaturated fatty acid metabolism in fibroblasts

open access: yesThe FASEB Journal, Volume 39, Issue 5, 15 March 2025.
Human adenovirus serotype 5 was used to infect HEK293 fibroblasts at low MOI (0.5, 1.0, and 2.0). Infected cells were interrogated by gas chromatography time‐of‐flight mass spectrometry (GC‐TOF‐MS) at 6, 12, 24, and 36 h post‐infection. The total metabolites were evaluated using an untargeted analysis of primary carbons. The results indicate a decrease
Bailey‐J C. Sanchez   +2 more
wiley   +1 more source

Nexus between CSR and DSIW: A PLS-SEM Approach

International Journal of Hospitality Management, 2020
Abstract Various studies have acknowledged the significance of “Corporate Social Responsibility” (CSR) for enhancing organizational performance. However, less is known about it’s micro-level impact on employees’ working behavior, including employees’ “Desire to have a Significant Impact through Work” (DSIW) in the airline industry.
Muhammad Shoaib Farooq, Maimoona Salam
openaire   +2 more sources

When to use and how to report the results of PLS-SEM [PDF]

open access: possibleEuropean Business Review, 2019
PurposeThe purpose of this paper is to provide a comprehensive, yet concise, overview of the considerations and metrics required for partial least squares structural equation modeling (PLS-SEM) analysis and result reporting. Preliminary considerations are summarized first, including reasons for choosing PLS-SEM, recommended sample size in selected ...
Marko Sarstedt   +3 more
openaire   +1 more source

Applying the PLS-SEM Model for the Loyalty of Domestic Travelers

2021
The purpose of this paper builds a model for the loyalty of domestic travelers. We gathered research data from 345 consumers in Nha Trang City, Khanh Hoa Province, Vietnam. The research model was proposed from previous researches. Besides, we applied the partial least squared structural equation modeling (PLS-SEM) with SmartPLS software for data ...
Bui Huy Khoi   +2 more
openaire   +2 more sources

A PLS-SEM Approach to Technology-Enhanced EFL Writing

2020 IEEE International Conference on Teaching, Assessment, and Learning for Engineering (TALE), 2020
This paper aims to examine game-based learning assisted by Google Classroom in EFL writing course. By facilitating effective participation for teachers and students, Google Classroom is improving to be a mature teaching console in initiating learning strategies, enhancing learning effects and leveraging online teaching resources.
openaire   +2 more sources

Treating Unobserved Heterogeneity in PLS-SEM: A Multi-method Approach

2017
Accounting for unobserved heterogeneity has become a key concern to ensure the validity of results when applying partial least squares structural equation modeling (PLS-SEM). Recent methodological research in the field has brought forward a variety of latent class techniques that allow for identifying and treating unobserved heterogeneity. This chapter
Marko Sarstedt   +4 more
openaire   +2 more sources

Workplace spirituality and knowledge hiding behaviour: a PLS-SEM analysis

International Journal of Business Information Systems, 2021
Shafique Ur Rehman   +2 more
openaire   +2 more sources

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