Results 91 to 100 of about 549,751 (378)

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Factors Affecting Satisfaction and Loyalty in Public Transport using Partial Least Squares Structural Equation Modeling (PLS-SEM)

International Journal of Innovative Technology and Exploring Engineering, 2019
With an increasing number of privately own vehicles in Malaysia, the popularity of public transports is increasingly challenged by ride-hailing services such as Grab, MyCar, JomRides and MULA.
Y. Mah, Bin Hashim., M. Lo, Shiaw-Tong Ha   +3 more
semanticscholar   +1 more source

Implementing PLS for distance-based regression: computational issues [PDF]

, 2006
Distance-based regression allows for a neat implementation of the Partial Least Squares recurrence. In this paper we address practical issues arising when dealing with moderately large datasets (n ~ 10^4) such as those typical of automobile insurance ...
Boj, Eva, Claramunt, M. Merce, Fortiana, Josep, Grané, Aurea   +3 more
core   +1 more source

Multi-view predictive partitioning in high dimensions

, 2012
Many modern data mining applications are concerned with the analysis of datasets in which the observations are described by paired high-dimensional vectorial representations or "views".
McWilliams, Brian, Montana, Giovanni
core   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Les caractéristiques individuelles et du voyage des migrants subsahariens au Maroc et le risque - Analyse par la Méthode PLS

, 2022
ECHRIDI Elghalia, Rachid Chaabita
openalex   +1 more source

Strategy Development Analysis in Supply Chain Management in 3PL Service Industry Using PLS-SEM [PDF]

, 2023
Syahnaz Aulia, P Dendi
openalex   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Wavelengths selection based on genetic algorithm (GA) and successive projections algorithms (SPA) combine with PLS regression for determination the soluble solids content in Nam-DokMai mangoes based on near infrared spectroscopy

Engineering and Applied Science Research, 2022
The objective of this work was to search for an optimal wavelength selection for near infrared (NIR) spectroscopy for quality measurement of Nam-Dokmai mangoes. In this study, NIR spectroscopy has been applied to grading management systems for commercial
Kanvisit Maraphum, Artjima Ounkaew, Pornnapa Kasemsiri, Salim Hiziroglu, Jetsada Posom   +4 more
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