Results 171 to 180 of about 331,997 (287)

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

Advanced Science, EarlyView.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu, Jiajia Zhuo, Xiaoquan Hong, Shihao Rao, Yafang Ye, Dandan Kang, Huifang Peng, Huiqin Zhuo   +7 more
wiley   +1 more source

A Case of Mucus Plug Removal via Bronchoscopy Using a Larger-Sized Endotracheal Tube in a Child With Plastic Bronchitis. [PDF]

Cureus
Gotou T, Hagihara T, Wada Y, Hashimoto K.   +3 more
europepmc   +1 more source

AI‐Assisted Self‐Powered Wearable Dual‐Mode Sensor With TENG and Stretchable Optical Fiber for Neurological Disorder Diagnostics

Advanced Science, EarlyView.
This manuscript presents the WDMS platform, an AI‐assisted, self‐powered wearable dual‐mode sensor for tele‐neurology. It integrates a contact–separation TENG insole with stretchable polyurethane optical‐fiber strain sensors to synchronously track plantar pressure and lower‐limb muscle deformation.
Tianliang Li, Han Liu, Guoxu Liu, Qian'ao Wang, Haotian Zhou, Guiyi Liu, Yan Xu, Jun Wang, Zuqiang Wang, Feng Zhu, Feiling Luo, Zhong Lin Wang, Chi Zhang   +12 more
wiley   +1 more source

Clinical Impact of Mepolizumab on Airway Mucus Plugs in Patients with Severe Asthma. [PDF]

J Asthma Allergy
Hara Y, Tanabe N, Marumo S, Murohashi K, Hayashi Y, Nagata M, Asada T, Nagaoka S, Kobayashi N, Hirai T, Kaneko T.   +10 more
europepmc   +1 more source

A Reliable Strategy to Unravel the Structure and Composition of Semiconducting Conjugated Donor‐Acceptor Block Copolymers

Advanced Science, EarlyView.
This work proposes a reliable strategy to elucidate the structure and composition of conjugated donor‐acceptor block copolymers. The method, based on NMR analysis, allows to extract key structural information such as the number of heterojunctions (NoH) and the number of blocks (NoB) of the copolymers.
Antoine Curé, Pierre‐Alain Bayle, Lucie Rivet, Yann Kervella, Renaud Demadrille, Cyril Aumaître   +5 more
wiley   +1 more source

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source

Design and experiment of an automatic seedling pick-up device for strawberry transplanter. [PDF]

Sci Rep
Kang J, Ji D, Tian S, Liu S, Sheng T, Du G.   +5 more
europepmc   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Evaluation of Microleakage of an Orthograde Apical Plug of Mineral Trioxide Aggregate and Biodentine in Permanent Teeth with Simulated Immature Apices: An <i>In Vitro</i> Study. [PDF]

J Pharm Bioallied Sci
Bhardwaj M, Metgud S, Bhavana Koushik BS, Maheshwari V, Sharma A, Mishra SK.   +5 more
europepmc   +1 more source

Tunable Plug‐and‐Play Meta‐Nanogenerator Materials for Multi‐Range Force Measurements

Advanced Science, EarlyView.
The multifunctional and tunable meta‐nanogenerator material system combines a mechanical metamaterial and a triboelectric nanogenerator enabling self‐powered, real‐time force sensing across application‐specific ranges. Geometrical tuning adjusts stiffness and the force sensing range, while modular integration streamlines assembly.
Roshira Premadasa, Pouya Almasi, Samriddhi Ghimire, Wenkui Dong, Chenjie Zhang, Pengcheng Jiao, Qianyun Zhang   +6 more
wiley   +1 more source