Results 251 to 260 of about 369,948 (336)

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Embolization of a wide-necked aneurysm of the renal artery ostium using an Amplatzer vascular plug 2: a case report. [PDF]

CVIR Endovasc
Ghosn M, Derbel H, Zaarour Y, Wei F, Tacher V, Kobeiter H.   +5 more
europepmc   +1 more source

3D‐Printed Architected Anisotropic Channels for Ultrafast Solar‐Driven Interfacial Evaporation via Localized Thermal Management and Water Layer Structuring

Advanced Science, EarlyView.
A 3D‐printed anisotropic channel evaporator integrates directional geometry with aligned titanium oxide, boron nitride, and chitosan networks to coordinate photon absorption, heat localization, and water transport. Phonon‐guided thermal pathways and interfacial water structuring enable ultrahigh evaporation rates and long‐term salt‐resistant solar ...
Sijia Sun, Dong Jiang, Hengsong Zheng, Shuai Zhang, Ziyuan Cheng, Changtong Mei, Dan Tian, Shilong Yang, Yusuke Yamauchi, Mingzhu Pan   +9 more
wiley   +1 more source

Influence of Novel "Umbrella"-Type Ladle Shroud on Liquid Steel Flow in a Two-Strand Slab Tundish: Physical and Numerical Modelling. [PDF]

Materials (Basel)
Cwudziński A, Fogaraš L, Demeter J, Demeter P, Buľko B.   +4 more
europepmc   +1 more source

Geochemical and petrographic evaluation of hydrous pyrolysis experiments on core plugs of Lower Toarcian Posidonia Shale: Comparison of artificial and natural thermal maturity series

Arysthasya Arysanto, Linda Burnaz, Tianyu Zheng, Ralf Littke   +3 more
openalex   +1 more source

Bioorthogonal Sonodynamic Plug‐and‐Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation

Advanced Science, EarlyView.
Bioorthogonal SDPTAC harnesses US‐responsive Ce6‐TCO and Tz ligands via IEDDA click chemistry to assemble degraders in situ, generating ROS that selectively eliminate nuclear, cytosolic, and membrane proteins, thereby suppressing deep‐seated tumors in vivo.
Yuhan Bao, Yaojin Zhu, Xinhao Wei, Yuxin Fang, Jiayi Zhu, Fei Gao, Guoqiang Dong, Shipeng He, Chunquan Sheng   +8 more
wiley   +1 more source

Antithrombotic Therapy After Percutaneous Left Atrial Appendage Closure: Results From the TERMINATOR Registry. [PDF]

JACC Asia
Sugiyama Y, Matsumoto T, Kubo S, Nakajima Y, Fukunaga M, Shimizu K, Ochiai T, Mizuno S, Kondo Y, Sugane H, Okubo K, Nakagawa K, Nagatomo D, Hachinohe D, Kusa S, Umemoto T, Nanasato M, Arita T, Yamasaki H, Kuwabara K, Yoshiyama T, Tanaka N, Masuda M, Sakamoto T, Nakashima M, Ohno Y, Saito S, Hara H.   +27 more
europepmc   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Long-term outcome following endovascular repair of complex aortocaval fistula after nephrectomy. [PDF]

J Vasc Surg Cases Innov Tech
Zielke T, Sansone J, Madison M, Aridi H, Gupta A, Motaganahalli R.   +5 more
europepmc   +1 more source

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source