Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee +4 more
wiley +2 more sources
3D CT-Based quantification of airway structural changes during asthma exacerbations: a retrospective observational study. [PDF]
Ozoe R +17 more
europepmc +1 more source
Systematic Review of Females With Intellectual Disability and MECP2 Duplication
ABSTRACT MECP2 Duplication Syndrome (MDS) is a rare, X‐linked neurodevelopmental disorder typically affecting males. Females with MDS have been reported and are compiled here. We conducted a systematic review (PROSPERO CRD420250652426) of PubMed, EMBASE, and Google Scholar extracting individual participant data.
Paul Malik +10 more
wiley +1 more source
CONSISTENCY MODELS FOR FAST MRI USING REGULARIZATION BY DENOISING. [PDF]
Gülle M +3 more
europepmc +1 more source
Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified.
Ionuț‐Flavius Bratu +5 more
wiley +1 more source
High resolution, contrast-enhanced X-ray microscopy of the <i>ex vivo</i> human cochlea: technical feasibility and biometric case analysis. [PDF]
Jang SS +4 more
europepmc +1 more source
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang +12 more
wiley +1 more source
Growth Promotion of Delayed-Transplanted Strawberry Plug Seedlings by Single- and Combined-Strain Inoculation of <i>Bacillus</i> spp. [PDF]
Liu F +5 more
europepmc +1 more source
Grid carbon intensity drives the electricity-related carbon footprint of robot-assisted radical prostatectomy: a cross-jurisdiction modelling study. [PDF]
Drobot RB.
europepmc +1 more source
Finite-Resolution Information from Collision Statistics. [PDF]
Gates AJ.
europepmc +1 more source

