Results 111 to 120 of about 72,973 (252)
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
Architectural Vulnerabilities in Plug-and-Play Systems
, 2018 Plug-and-play architectures enhance systems’ extensibility by providing a framework that enables additional functionalities to be added or removed from the system at their runtime.
Corrello, Taylor
core
Plug-and-Play Module for Reversible and Continuous Control of DNA Strand Displacement Kinetics
Regulatory modules for controlling the kinetics of toehold-mediated strand displacement (TMSD) play critical roles in designing dynamic and dissipative DNA chemical reaction networks (CRNs) but are hardwired into sequence designs.
Guan A. Wang (6883655) +2 more
core +1 more source
Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors
Advanced Science, EarlyView.This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung +7 more
wiley +1 more source
Toward Plug and Play Myoelectric Control via One-Shot Latent Representation Alignment
IEEE Transactions on Neural Systems and Rehabilitation EngineeringMyoelectric control has emerged as a common tool for human-machine interaction with applications in prostheses, rehabilitation, and mixed reality. Despite the growing research and promising results in controlled laboratory settings, there are challenges ...
Zubaidah Al-Mashhadani +3 more
doaj +1 more source
Advanced Science, EarlyView.A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma +6 more
wiley +1 more source
Plug-and-Play Virtual Factories
, 2012 Although virtual factories are a well-established approach to managing distributed, cross-organizational manufacturing processes, corresponding end-to-end IT support is still lacking.
Schuller, Dieter +3 more
core +1 more source
Advanced Science, EarlyView.A biomimetic artificial extracellular matrix is assembled directly on Pseudomonas fluorescens by co‐assembling amyloid‐like lysozyme and alginate at the cell surface. This conformal nanocoating acts as both a hydration buffer and a physiological priming layer, markedly enhancing desiccation tolerance, seed adhesion, storage stability, and biocontrol ...
Yuanyuan Wang +5 more
wiley +1 more source
Over the preceding eight months, the Master of Architecture students at Northumbria University have looked behind the public facade of NewcastleGateshead, reading the rich palimpsest they found there and embracing the appropriation of spaces left hidden ...
Messer, Sebastian
core
Discriminator‐Guided Inverse Folding for Multi‐Property Protein Design
Advanced Science, EarlyView.Discriminator‐Guided Inverse Folding (DGIF) integrates multiple property predictors trained from single‐property datasets to guide protein sequence generation from a backbone structure. DGIF enables simultaneous improvement of thermostability and solubility without requiring multi‐property annotated datasets and generates designs that move toward the ...
Yuchuan Zheng +7 more
wiley +1 more source