Results 71 to 80 of about 2,590 (179)

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

open access: yesCell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou   +8 more
wiley   +1 more source

Climate Uncertainty and Financial Subordination: Evidence From a Two‐Country Stock‐Flow Consistent Model

open access: yesEuropean Financial Management, EarlyView.
ABSTRACT In the face of climate change, uncertainty is deep, systemic, and does not propagate amid an institutional vacuum, contrary to assumptions often underlying existing macroeconomic climate models. The paper presents a macroeconomic Stock‐Flow Consistent model to examine the impact of climate‐related financial pressures under fundamental ...
Riccardo D'Orsi
wiley   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

open access: yesThe FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari   +7 more
wiley   +1 more source

Mind the gap: a prospective observational study of interprofessional differences in ASA-PS assessments between surgeons and anaesthesiologists. [PDF]

open access: yesBMC Anesthesiol
El Youzouri H   +11 more
europepmc   +1 more source

Never Mind the Bollards: Exploring the Role of GCHQ, MI5, and the National Technical Authorities in UK Security Markets

open access: yesThe Howard Journal of Crime and Justice, EarlyView.
ABSTRACT The cultures and governance of security markets in the United Kingdom are often characterised through a paradoxical narrative of simultaneous state retreat and progressive advance. In the face of repeated recent high‐profile security failures, and global changes in material political economy, we argue that UK security governance is adapting to
Ben Collier, Jamie Buchan
wiley   +1 more source

Lung Ultrasound-Guided Non-Fiberobronchoscopic Bronchoalveolar Lavage for Neonatal Atelectatic Pulmonary Disease Treatment: Clinical Practice Guidelines Based on International Expert Consensus. [PDF]

open access: yesDiagnostics (Basel)
Liu J   +41 more
europepmc   +1 more source

‘You Wish You Could Do More, but You Just Can't’: The Hidden Harms of Casework With Justice‐Involved Women

open access: yesThe Howard Journal of Crime and Justice, EarlyView.
ABSTRACT Caseworkers in women's centres in the United Kingdom provide support to justice‐involved women. They do so amidst an unpredictable funding landscape shaped by austerity, resulting in underfunded and overstretched public services. As part of the penal voluntary sector, women's centres have stepped forward, providing frontline support to women ...
Kelly Mackenzie   +2 more
wiley   +1 more source

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