Results 31 to 40 of about 4,144,262 (288)
OBJECTIVE: To evaluate the clinical and radiographic response of the lumbar curve after fusion of the main thoracic vertebrae, in patients with adolescent idiopathic scoliosis of Lenke type 1.
Danilo Mizusaki +1 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Pendulum Rule versus Spinopelvic Parameters how the Explain the Sagittal Shape of the Spine?
Introduction Usually, the analysis of the spinal sagittal shape is based on a vertebral semantic, focusing on the curves (lordosis, kyphosis) and the spinopelvic parameters (pelvic incidence, sacral slope, pelvic tilt, sagittal balance).
Gilles Norotte
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Latar belakang : Skoliosis merupakan keadaan tulang belakang mengalami abnormalitas kelengkungan kurva ke sisi lateral pada bidang frontal dan dengan atau pun tidak disertai rotasi tulang belakang pada bidang sagital dan axial.
Adillah Nur Afifah +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Letter from Preston B. Plumb to Cavaness, 1891 November 4
A letter on Emporia State Bank letterhead from Preston B. Plumb to Cananess regarding general matters, dated November 4, 1891.Archival master image scanned in reflective mode as 48-bit RGB color TIFF using Epson 11000XL.
Plumb, Preston B., 1837-1891
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Letter from Preston B. Plumb to Cavaness, 1886 December 10
A letter on Senate Chamber letterhead from Preston B. Plumb to Cavaness regarding money owed, dated December 10, 1886.Archival master image scanned in reflective mode as 48-bit RGB color TIFF using Epson 11000XL.
Plumb, Preston B., 1837-1891
core +1 more source

