Results 251 to 260 of about 173,543 (315)

Bioactive Magnesium Silicate Activating Myocardial Energy Metabolism For Infarcted Myocardium Repair

Exploration, EarlyView.
ABSTRACT The heart is a highly energy‐dependent organ, developing bioenergy‐activating biomaterials to activate myocardial adenosine triphosphate (ATP) production and restore dysregulated energy homeostasis is a promising solution for its functional recovery.
Zhibin Liao, Chen Qin, Erhong Song, Chengbin Ding, Zhixu Wang, Yan Sun, Chen Song, Junjie Liu, Jingge Ma, Hongjian Zhang, Leyu Wang, Chengtie Wu   +11 more
wiley   +1 more source

Generation of functionally competent testicular somatic cells from pluripotent stem cells. [PDF]

Sci Adv
Sato T, Yoshino T, Ohtsuka M, Suzuki T, Matsumura T, Matsudaira Y, Ishikawa-Yamauchi Y, Maeda S, Yabukami H, Kanai Y, Inoue M, Shima Y, Tachibana M, Matoba S, Inoue K, Ogonuki N, Ogura A, Hayashi K, Ogawa T.   +18 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Universal conditional knockout approach to multiple species, from fish to human induced pluripotent stem cells. [PDF]

Nucleic Acids Res
Choi JH, Moon J, Oh Y, Klompstra TM, Kim Y, Baek G, Kwak Y, Kim Y, Lee S, Park S, Ha J, Kwon O, Choi YK, Kim JH, Lee JH, Park J, Kim JK, Woo DH, Yoon KJ, Koo BK, Lee H.   +20 more
europepmc   +1 more source

Roles of histone lysine methylation in neurodevelopment and related disorders

Ibrain, EarlyView.
This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen, Yi Zhang, Hong Zhang, Xiaoli Liang   +3 more
wiley   +1 more source

Advances in the differentiation of induced pluripotent stem cells into vascular cells for the treatment of diabetic microvascular disease. [PDF]

Cardiovasc Diabetol
Wang S, Zhong H, Wu Y, Zhang Y, Sha A, Zhu Z, Fang X, Bao M, Sun D.   +8 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Correction: Generation of Human Melanocytes from Induced Pluripotent Stem Cells. [PDF]

PLoS One
Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y.   +10 more
europepmc   +1 more source