Results 251 to 260 of about 1,024,717 (349)

Droplet microfluidics: Enabling the tailored fabrication of hydrogel particles

Droplet, EarlyView.
Droplet microfluidics enables precise, versatile fabrication of hydrogel particles with controlled size, composition, and structure. This review summarizes fundamental principles, engineering strategies, and emerging applications, providing a framework for advancing microfluidic hydrogel technologies.
Zhongqiao Gan, Xu Hou
wiley   +1 more source

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

Nature Biotechnology, 2008
Danwei Huangfu, R. Maehr, Wenjun Guo, A. Eijkelenboom, Melinda E. Snitow, Alice E. Chen, D. Melton   +6 more
semanticscholar   +1 more source

Post-transcriptional control of endogenous retroviruses by L1td1 suppresses totipotency acquisition in pluripotent stem cells. [PDF]

Cell Discov
Wu Y, Liu Y, Huang Y, Hao Z, Li W, Li Y, Zhang M, Li L, Qin D, Chen K, Liu X.   +10 more
europepmc   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Generation of Intestinal and Colonic Organoids Derived From Human Pluripotent Stem Cells. [PDF]

Biol Cell
Bonneau L, Brossard L, Noël T, Perreaux V, Bachir L, Khan A, Vales S, Mahe MM.   +7 more
europepmc   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Protocol for generating megakaryocytes from patient induced pluripotent stem cells for disease modeling and compound screening. [PDF]

STAR Protoc
Chawla P, Flosdorf N, de Toledo MAS, Zenke M.   +3 more
europepmc   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Exiting the ground state: the broad spectrum of cell fates accessible from naïve human pluripotent stem cells. [PDF]

Cell Mol Life Sci
Park KM, Yin R, Theunissen TW.
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source