Results 131 to 140 of about 156,323 (302)

Transforming acute exacerbations of chronic obstructive pulmonary disease (AECOPD) risk assessment: A multi‐algorithm machine learning approach for precise clinical phenotyping

VIEW, EarlyView.
We addressed the clinical need for individualized early identification of AECOPD by analyzing a longitudinal cohort of 878 COPD patients (20072024) and benchmarking 91 algorithms, yielding an interpretable ensemble model (AECOPD‐RS). The model showed strong performance (C‐index 0.815; validation 1/3/5‐year AUCs 0.864/0.865/0.855), with SHAP/VIMP ...
Yiqun Dong, Junyi Shen, Chaofan Fan, Anqi Lin, Peng Luo, Xin Chen   +5 more
wiley   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Impacts of energy efficiency retrofitting measures on indoor PM concentrations across different income groups in England: a modelling study [PDF]

, 2015
As part of an effort to reduce carbon emissions in the UK, policies encouraging the energy-efficient retrofit of domestic properties are being implemented. Typical retrofits, including installation of insulation and double glazing can cause tightening of
Das, P, Davies, M, Hamilton, IG, Oikonomou, E, Shrubsole, C, Taylor, J   +5 more
core  

The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Environmental pollution and climate change seriously affect human health, leading to the onset and exacerbation of chronic respiratory diseases, such as allergic rhinitis and lung diseases. Over the past several decades, increasing air pollution and environmental exposure owing to global urbanization, industrialization, and rapid economic ...
Xin‐Yan Liu, Rui‐Ming Han, Yong‐Tai Wang, Dong‐Dong Zhu, Cui‐Da Meng   +4 more
wiley   +1 more source

Exposure to PM2.5 affects blood lipid levels in asthmatic rats through notch signaling pathway [PDF]

, 2019
Tianrong Zhang, Yan Zheng, Yizhen Gao, Tianyang Zhao, Shuangyu Guo, Liwei Yang, Yanbin Shi, Liting Zhou, Lin Ye   +8 more
openalex   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Vog: Using Volcanic Eruptions to Estimate the Health Costs of Particulates

The Economic Journal, EarlyView., 2018
The negative consequences of long‐term exposure to particulate pollution are well established but a number of studies find no effect of short‐term exposure on health outcomes. The high correlation of industrial pollutants complicates the estimation of the impact of individual pollutants on health.
Timothy J. Halliday, John Lynham, Áureo de Paula   +2 more
wiley   +1 more source

Characterization of Respirable Particulate Matter Collected With Cyclones in School Environments of the Metropolitan Region of Rio de Janeiro

X-Ray Spectrometry, EarlyView.
ABSTRACT The relevance of investigating atmospheric particulate matter (PM) in the school environment is related to its significant impact on the health of school‐age children. In this context, the present study focuses on the characterization of suspended atmospheric PM in eight elementary schools located in the metropolitan region of Rio de Janeiro ...
J. L. Pereira, F. T. S. Tsuyama, Hamilton S. G. Filho, R. Leitão, C. G. L. Canellas, J. T. Assis, M. J. Anjos   +6 more
wiley   +1 more source

PM2.5 Chemical Composition and Geographic Origin of Air Masses in Mabopane, South Africa

X-Ray Spectrometry, EarlyView.
ABSTRACT Air pollution is a major global threat to health. The study aimed to analyze the chemical composition of PM2.5 in Mabopane, South Africa, and to identify the contribution of transported particulate pollution sources using backward air transport cluster analysis.
Mandla Bhuda, Peter Molnár, Johan Boman, Joyce Shirinde, Janine Wichmann   +4 more
wiley   +1 more source

Application of deep learning techniques for analysis and prediction of particulate matter at Kota city, India

EQA
Air pollution significantly threatens human health and the environment, making accurate prediction of pollutant concentrations crucial for effective mitigation.
Lovish Sharma, Hajari Singh, Mahendra Pratap Choudhary   +2 more
doaj   +1 more source