Results 151 to 160 of about 2,274,005 (214)

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo, Guohua Yu, Huixia Fan, Ruofan Guo, Jingqi Zheng, Chen Wang, Ruyi Jin, Junhui Zhou, Jian Yang   +8 more
wiley   +1 more source

A MassQL‐Based Framework for Rule‐Guided MS/MS Class‐Level Retrieval and Analog Discovery of Cannabinoids

Rapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Cannabinoids comprise a chemically diverse group of meroterpenoids whose extensive isomerism, variable side‐chain length, and frequent oxidative or rearranged derivatives lead to strongly overlapping yet characteristic MS/MS fragmentation patterns. In untargeted LC–MS/MS datasets, this combination of structural diversity and spectral
Julia Maia Galvão de Queiroz, Fernanda Oliveira Chagas, Valdir Florêncio Veiga‐Júnior, Monica Costa Padilha, Ricardo M. Borges   +4 more
wiley   +1 more source

Repeatability of Metabolic Imaging With Hyperpolarized Pyruvate: Back‐to‐Back Neuroimaging and Blood Analysis

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 548-556, August 2026.
ABSTRACT Purpose 13C MRI with hyperpolarized [1‐13C]pyruvate enables noninvasive imaging of metabolic pathways. Considering the high dose of pyruvate used in hyperpolarized 13C‐pyruvate studies, circulating 13C‐pyruvate and the resulting 13C‐lactate in plasma may influence subsequent pyruvate metabolism, yet the guidance on consecutive injections does ...
Jun Chen, Sung‐Han Lin, Jessica Sudderth, Kelley A. Derner, Crystal E. Harrison, Maheen Zaidi, Jeannie D. Baxter, Jeff Liticker, Zohreh Erfani, Craig R. Malloy, Marco C. Pinho, Ralph J. DeBerardinis, Jae Mo Park   +12 more
wiley   +1 more source

A 3‐Month Follow‐Up Pilot Study on Accelerated Intermittent Theta Burst Stimulation for Bipolar Depression

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Approximately 25% of patients with bipolar disorder are reported to have treatment‐resistant bipolar depression (TRBD). Accelerated intermittent Theta Burst Stimulation (aiTBS) is an innovative form of repetitive transcranial magnetic stimulation (rTMS), delivering bursts of stimulation at theta wave frequencies, which are believed ...
Daan Neuteboom, Urmi Pahladsingh, Martijn C. Steinbach, Marjan C. Ploegaert, Jasper B. Zantvoord, Anja Lok, Lieuwe de Haan, Karel W. F. Scheepstra   +7 more
wiley   +1 more source

Bank IPOs and Regulations: Cross‐Country Evidence

Financial Review, Volume 61, Issue 3, Page 867-899, August 2026.
ABSTRACT The present paper investigates the effect of banking industry regulations on bank initial public offering (IPO) underpricing. We approach this question from both a micro‐level and macro‐level regulatory perspective. First, we conduct our analysis within a micro framework, focusing on the effect of disclosure rules on IPO underpricing.
Maria‐Eleni K. Agoraki, Dimitrios Gounopoulos, Georgios P. Kouretas   +2 more
wiley   +1 more source

How to evaluate rare disease policy effectiveness based on policy modeling consistency (PMC) index model: A quantitative assessment of policy implementation in China. [PDF]

Intractable Rare Dis Res
Zhao Y, Zhang X, He D, Li Y, Dong R, Gu Y, Xie J.   +6 more
europepmc   +1 more source

Developmental Profile and Variability in Preschool‐Age Children With Down Syndrome

Journal of Intellectual Disability Research, Volume 70, Issue 8, Page 881-886, August 2026.
ABSTRACT Background The developmental and cognitive profile of Down syndrome (DS) has been studied across various age groups, but we have still a limited understanding of the preschool‐age range, including the domains that show the greatest variability at this age. Our study aims to (1) define the developmental profile in preschool‐age children with DS
Sara Onnivello, Giuseppe Ramacieri, Elisa Rossi, Maria Chiara Pelleri, Francesca Antonaros, Sara Colaianni, Chiara Marcolin, Francesca Pulina, Beatrice Vione, Francesca Catapano, Enrico Toffalini, Chiara Locatelli, Pierluigi Strippoli, Silvia Lanfranchi   +13 more
wiley   +1 more source

Wood‐Derived Sphere‐Like Biochar Granules as an Electrode Platform for Future Bed Electrodes

ChemElectroChem, Volume 13, Issue 14, 17 July 2026.
Wood‐derived, sphere‐like granular biochar (GB) modified with NiMo is introduced as a potential cathode platform for the hydrogen evolution reaction at neutral pH for use in CO2‐reducing bioelectrochemical systems. They exhibit remarkably higher electrocatalytic activity, making wood‐derived sphere‐like GB a promising stackable cathode material for ...
Shabnam Pouresmaeil, Jan Griebel, Andrea Prager, Falk Harnisch, Jörg Kretzschmar   +4 more
wiley   +1 more source

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann, Milena Carolina Paz, Paola Sônego, Ana Carolina Contri Natal, Lívia Surita, Marcele Bettim Bandinelli, Luciana Sonne   +6 more
wiley   +1 more source

Alteration of a Mantle‐Derived Dunite Boulder in Jezero Crater, Mars

Geophysical Research Letters, Volume 53, Issue 13, 16 July 2026.
Abstract In 2023, the Mars 2020 Perseverance rover explored the youngest preserved deposits on the Western fan of Jezero crater, Mars: a field of meter‐scale boulders dispersed above the previously explored sandstone and siltstone units. Reflectance spectra of the boulders delineated two classes, one olivine‐bearing and one pyroxene‐bearing.
E. L. Moreland, M. Bramble, K. L. Siebach, A. C. Pascuzzo, M. Morris, S. J. VanBommel, M. Jones, S. Siljeström, A. Srivastava, A. H. Treiman, J. Hurowitz   +10 more
wiley   +1 more source