Results 121 to 130 of about 2,387 (173)

DPIs cannot replace pMDIs in the management of obstructive airways disease

Canadian Journal of Emergency Medicine
openaire   +2 more sources

Clearing the air: a systematic review on leadership challenges with sustainable inhaler prescribing. [PDF]

BMJ Lead
Kajitani S, Goodings A, Richa Y, Babun AA, Chhor A, Velasco R, Trujillo J.   +6 more
europepmc   +1 more source

Costs of Single Maintenance and Reliever Therapy vs Traditional Therapy for Asthma.

JAMA Netw Open
Pham T, Barker AR, Eisenstein SA, Jost E, Volerman A, Chauhan K, Brownson RC, McBride T, Huffman MD, Sumino K, Gerald LB, Castro M, Dixon AE, Krings JG.   +13 more
europepmc   +1 more source

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Novel pMDI formulations for pulmonary delivery of proteins

International Journal of Pharmaceutics, 2010
In this paper, we demonstrate that co-spray-drying a model protein with sodium carboxymethylcellulose (NaCMC) protects protein integrity during spray-drying, and that the resultant spray-dried powders can be successfully dispersed in hydrofluoroalkane (HFA) propellant to prepare pressurised metered dose (pMDI) formulations that exhibit high respirable ...
Peter Seville
exaly   +3 more sources

Bronchoprotective and Bronchodilator Effects of an HFA pMDI vs. a CFC pMDI and a DPI Containing Formoterol in Asthma Patients

Respiration, 2005
In this double-blind, placebo-controlled, crossover study we compared the bronchoprotective effects of formoterol 12 µg inhaled via an HFA-134a inhaler (Modulite^® HFA) versus a CFC and a DPI device in 38 patients with mild-to-moderate persistent asthma.
Singh, Sukh, Langley, S. J., Houghton, C. M., Singh, S. D.   +3 more
openaire   +3 more sources

Plume characteristics of fluticasone propionate/formoterol pMDI compared with fluticasone propionate/salmeterol pMDI

European Respiratory Journal, 2013
Background It has been suggested that aerosol inhaler characteristics such as fine particle size distribution, low plume velocity, and long duration of the aerosol cloud may assist coordination of inhalation with actuation, improve lung deposition, and reduce oropharyngeal ...
Baljinder Johal, Seamus Murphy, Jonathan Marshall   +2 more
openaire   +1 more source

Plume temperature and force of fluticasone propionate/formoterol pMDI compared with fluticasone propionate/salmeterol pMDI

European Respiratory Journal, 2014
Background: Aerosol inhaler characteristics such as low plume temperature and high force may result in greater impaction of drug in the mouth and throat and reduced lung deposition.
Baljinder Johal, John Tuohy, Jonathan Marshall   +2 more
openaire   +1 more source

Comparative Effect of Biofillers in pMDI Resin Performance

Forest Products Journal, 2023
Abstract This study investigated the feasibility of using wood flour (WF) as a partial substitute in polymeric methylene diphenyl diisocyanate (pMDI) resin and compared its performance with soy flour (SF) substituted in pMDI resin. The physical and mechanical properties of experimental particleboards made with WF and SF substituted in pMDI ...
Abiodun Alawode, Femi Kehinde Owofadeju, Munkaila Musah, Osei Asafu-Adjaye, Brian Via   +4 more
openaire   +1 more source

HPFP, a Model Propellant for pMDIs

Drug Development and Industrial Pharmacy, 2003
A novel model propellant for the study of the properties of pMDIs (pressurized metered-dose inhalers) at atmospheric pressure is proposed and extensively characterized. The reasons for the choice of this liquid, with its advantages and drawbacks, are explained and justified. Comparison with existing fluorinated propellants is also documented.
openaire   +2 more sources