Results 11 to 20 of about 2,387 (173)

Global pMDI Use and the Potential Impact of European PFAS Legislation on Access to These Essential Inhaled Medications [PDF]

Pulmonary Therapy
Introduction Many essential inhaled medicines recommended in guidelines are delivered to the lung via pressurized metered-dose inhalers (pMDIs). Global environmental legislation will lead to phasing out of hydrofluoroalkane propellants currently used in ...
Janwillem W. H. Kocks, Tim Harrison, John P. Bell, Andy Rignall, Mina Khezrian, Omar S. Usmani   +5 more
doaj   +2 more sources

Salbutamol Reversal of Methacholine Induced Bronchoconstriction: Vibrating Mesh Nebulizer versus Pressurized Metered Dose Inhaler [PDF]

Journal of Asthma and Allergy
Beth E Davis, Brianne S Philipenko, Donald W Cockcroft Division of Respirology and Sleep Medicine, Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaCorrespondence: Beth E Davis, Division of Respirology and Sleep Medicine,
Davis BE, Philipenko BS, Cockcroft DW
doaj   +2 more sources

Trends in inhaler use and associated carbon footprint: a sales data-based study in Europe [PDF]

BMJ Open Respiratory Research
Background Physicians are being encouraged to favour dry powder inhalers (DPI) over pressurised metered dose inhalers (pMDI) on environmental grounds. The EU is reviewing the F-gas regulation to accelerate emission phase-down targets.
Lauri Lehtimäki, Christer Janson, Ville Vartiainen, Hanna Hisinger-Mölkänen, Alexander Wilkinson   +4 more
doaj   +2 more sources

Switching to the Dry Powder Inhaler: Disease Control with a Lower Carbon Footprint [PDF]

Pulmonary Therapy
Introduction Dry powder inhalers (DPIs) have a 20–40-fold lower carbon footprint compared to pressurized metered-dose inhalers (pMDIs). Switching from pMDI to DPI is therefore beneficial from an environmental perspective, but many health care ...
Christer Janson, Hanna Hisinger-Mölkänen, Lilla Tamasi, Ville Vartiainen, Lauri Lehtimäki   +4 more
doaj   +2 more sources

Efficacy and safety of budesonide/formoterol pMDI vs budesonide pMDI in asthmatic children (6–<12 years) [PDF]

Annals of Allergy, Asthma & Immunology, 2017
The efficacy and safety of budesonide/formoterol pressurized metered-dose inhaler (pMDI) have been demonstrated in patients with asthma at least 12 years old.To evaluate the efficacy of 2 formoterol doses added to budesonide as fixed combinations vs budesonide alone in children 6 to younger than 12 years with asthma.This randomized, double-blinded ...
Pearlman, David S., Eckerwall, Göran, McLaren, Julie, Lamarca, Rosa, Puu, Margareta, Gilbert, Ileen, Jorup, Carin, Sandin, Kristina, Lanz, Miguel J.   +8 more
openaire   +2 more sources

A CFD Study of a pMDI Plume Spray [PDF]

, 2014
Asthma is an inflammatory chronic disease characterized by airway obstructions disorders. The treatment is usually done by inhalation therapy, in which pressurized metered-dose inhalers (pMDIs) are preferred devices. The objective of this paper is to characterize and simulate a pMDI spray plume by introducing realistic factors through a computational ...
Oliveira, Ricardo Falcão, Ferreira, Ana C. M., Teixeira, S. F. C. F., Teixeira, J. Carlos, Marques, Helena C.   +4 more
openaire   +2 more sources

Therapeutic comparison of a new budesonide/formoterol pMDI with budesonide pMDI and budesonide/formoterol DPI in asthma.

International journal of clinical practice, 2007
Budesonide/formoterol is an effective treatment for both asthma and chronic obstructive pulmonary disease. This study compared the efficacy and safety of a novel hydrofluoroalkane (HFA) pressurised metered-dose inhaler (pMDI) formulation of budesonide/formoterol with that of budesonide pMDI and budesonide/formoterol dry-powder inhaler (DPI; Turbuhaler).
Morice, A H, Peterson, S, Beckman, O, Osmanliev, D   +3 more
openaire   +3 more sources

Twenty years of HFA pMDI patents: facts and perspectives [PDF]

Journal of Pharmacy and Pharmacology, 2012
Abstract Objectives Over the past 20 years, the inhalation drug delivery industry has undergone a quiet revolution after the phasing out of the chlorofluorocarbon propellants used to formulate pressure-metered dose inhalers (pMDIs).
Philippe, Rogueda, Arthur, Lallement, Daniela, Traini, Ilian, Iliev, Paul M, Young   +4 more
openaire   +2 more sources

Rapidly Diversifying Hydrogen‐Bonded Organic Frameworks With Permanent Porosity

Angewandte Chemie, EarlyView.
This article reviews diversifying hydrogen‐bonded organic frameworks (HOFs) with permanent porosity reported over the past 15 years, based on the molecular structures of their constituent tectons. Furthermore, several distinctive aspects and concepts are described, such as permanent porosity, isostructural (isoreticular) HOFs, and multicomponent mixed ...
Taito Hashimoto, Ichiro Hisaki
wiley   +2 more sources

Clinical outcomes of children using a metered dose inhaler with a sleeve attachment device to improve ease of use

Journal of Allergy and Clinical Immunology: Global, 2023
Background: Activating pressurized metered dose inhalers (pMDIs) is often challenging for children. The Easy Squeezy (ES) is a novel sleeve attachment device that reduces activation force by 3 times.
Kassim Babu Mapondela, MD, MMed (ENT), Roopam Dey, PhD, Michael Levin, MBChB, PhD   +2 more
doaj   +1 more source