Results 91 to 100 of about 36,715 (282)

Molecular Basis for Uracil‐DNA‐Glycosylase to Identify DNA Damage in the Nucleosome

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The DNA base‐excision repair (BER) pathway is initiated by a glycosylase, such as uracil‐DNA‐glycosylase (UDG), which identifies and removes a wrong base incorporated in the DNA sequence. The very early steps in the identification of the DNA damage are crucial to the correct initiation of the repair chain, and become even more complex when ...
Safwen Ghediri   +2 more
wiley   +1 more source

Despesas com a função saúde no município de Florianópolis, no período de 2004 a 2008 [PDF]

open access: yes, 2009
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisCom a finalidade de atender necessidades sociais, o Estado desenvolve os serviços públicos.
Rezende, Camila Schmitt
core  

Positive Matrix Factorisation (PMF) - An Introduction to the Chemometric Evaluation of Environmental Monitoring Data Using PMF [PDF]

open access: yes, 2009
Positive Matrix Factorization (PMF) is a multivariate factor analysis technique used successfully among others at the US Environmental Protection Agency for the chemometric evaluation and modelling of environmental data sets. Compared to other methods it
GAWLIK Bernd   +2 more
core   +1 more source

A Rank‐Based CUSUM Monitoring Scheme for Time Between Events and Amplitude Data

open access: yesQuality and Reliability Engineering International, EarlyView.
ABSTRACT Monitoring time between events and amplitude (TBEA) data is critical in many applications, particularly in manufacturing, reliability engineering, and service operations. Yet, most existing TBEA control charts focus on a single quality characteristic and are typically developed under restrictive distributional assumptions.
Muhammad Arslan   +5 more
wiley   +1 more source

Using MALDI‐FTICR Mass Spectrometry to Enhance ZooMS Identifications of Pleistocene Bone Fragments Showing Variable Collagen Preservation

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Recent advances in high‐throughput molecular analyses of collagen peptides, especially ZooMS (Zooarchaeology by Mass Spectrometry), have permitted breakthroughs in the analysis of archaeological material that is highly fragmented, a factor that hinders morphological identification.
Pauline Raymond   +8 more
wiley   +1 more source

Routing and Downlink Resource Allocation for Multicast Traffic in LEO Satellite Constellations

open access: yesInternational Journal of Satellite Communications and Networking, EarlyView.
ABSTRACT In this work, we optimize unicast and multicast traffic delivery over non‐terrestrial networks (NTNs) to users on the ground through direct satellite downlink (DL). We consider a gateway‐free mesh architecture with low Earth orbit (LEO) satellites interconnected via inter‐satellite links (ISLs), where unicast and multicast services compete for
Federico Lozano‐Cuadra   +3 more
wiley   +1 more source

Programmable 3D Microfluidics Reveals Motility‐Driven Antibiotic Resistance Evolution in Gradients

open access: yesSmall, EarlyView.
Using a programmable microfluidic platform, this study shows that bacterial motility is crucial for resistance development in heterogeneous antibiotic landscapes. Motile Escherichia coli randomly migrates along antibiotic gradients, and sufficient movement is required for resistance to emerge.
Xiaobo Li   +8 more
wiley   +1 more source

Predictive Amphiphile Design Enables Control of Self‐Assembled Nanoparticle‐Cell Membrane Interactions

open access: yesSmall, EarlyView.
The interactions of self‐assembled nanocarriers with cell membranes are programmable through amphiphile design. We identify how head and tail chemistry govern distinct interaction mechanisms and introduce ΔGtransfer, a unified thermodynamic descriptor that predicts nanoparticle behaviour from simple molecular simulations.
Mahsa Nami   +13 more
wiley   +1 more source

Different inflammatory, fibrotic, and immunologic signatures between pre-fibrotic and overt primary myelofibrosis

open access: yesHaematologica
Primary myelofibrosis (PMF) is a myeloid proliferative neoplasm (MPN) characterized by bone marrow (BM) fibrosis. Pre-fibrotic PMF (pre-PMF) progresses to overt PMF.
Seung-Hyun Jung   +6 more
doaj   +1 more source

Thrombospondin-1 (TSP-1) in primary myelofibrosis (PMF) — a megakaryocyte-derived biomarker which largely discriminates PMF from essential thrombocythemia

open access: yes, 2010
International audiencePrimary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm showing aberrant bone marrow remodeling with increased angiogenesis, progressive matrix accumulation, and fibrosis development.
Kreipe, Hans H.   +15 more
core   +1 more source

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