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Evaluation of statistical models of carriage to predict the impact of the 10-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in Nigeria

Adamu AL, Ojal J, Mburu C, Gallagher KE, Flasche S, Odeyemi K, Okoromah CA, Abubakar IS, Bello MM, Inem V, Karani A, Karia B, Akech D, Adetifa IM, Scott JAG.   +14 more
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Nationwide trends of invasive pneumococcal disease in Spain (2009-2019) in children and adults during the pneumococcal conjugate vaccine era.

Clinical Infectious Diseases, 2020
BACKGROUND Introduction of pneumococcal conjugate vaccines (PCVs) has shown a marked reduction in the disease caused by vaccine serotypes in children providing herd protection to the elderly group.
S. de Miguel, Mirian Domenech, F. González-Camacho, Julio Sempere, D. Vicioso, J. Sanz, Luis García Comas, C. Ardanuy, A. Fenoll, J. Yuste   +9 more
semanticscholar   +1 more source

Pneumococcal conjugate vaccines

Immunology Letters, 1991
We have prepared conjugates of pneumococcal type 4 polysaccharides (PS4) or oligosaccharides to tetanus toxoid using the carbodiimide method. The use of a spacer, 6-aminohexanoic acid, resulted in higher incorporation of carrier protein. Conjugates contained up to 10% free polysaccharide, but no free protein.
Bart L. Haagmans, Ger T. Rijkers, Dolf Evenberg, Ben J.M. Zegers, Anne-Marie Tenbergen-Meekes, Jan Poolman, Carla C. A. M. Peeters   +6 more
openaire   +2 more sources

Conjugated Heptavalent Pneumococcal Vaccine

The Annals of Pharmacotherapy, 2002
OBJECTIVE: To review the immunogenicity, efficacy, and safety of the heptavalent conjugated pneumococcal vaccine (PCV7). DATA SOURCES: A MEDLINE search (1993–August 2001) of research limited to humans published in the English language was conducted. STUDY SELECTION: Findings from randomized, controlled, multicenter trials were reviewed.
Vinita B. Pai, John Erramouspe, Catherine A Heyneman   +2 more
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The pneumococcal protein conjugate vaccines

The Journal of Pediatrics, 2000
to develop the first licensed pneumococcal vaccine, consisting of 14 purified capsular polysaccharide antigens representing the most prevalent disease-associated serotypes. Coverage was improved by the addition of 9 more purified polysaccharide antigens, resulting in the currently licensed 23valent pneumococcal capsular polysaccharide vaccine.
Timothy R. Peters, Kathryn M. Edwards
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Pneumococcal conjugate vaccine

Current Opinion in Pediatrics, 2001
Pneumococcal infections account for a significant proportion of bacterial infections in infants and children. The growing threat from pneumococci resistant to penicillin and other antimicrobials has led to increased pressure for the development of an effective vaccine.
openaire   +2 more sources