Results 71 to 80 of about 76,979 (321)

Elucidating the impact of the pneumococcal conjugate vaccine programme on pneumonia, sepsis and otitis media hospital admissions in England using a composite control

open access: yesBMC Medicine, 2018
BackgroundThe seven-valent pneumococcal conjugate vaccine (PCV) was introduced in England in September 2006, changing to the 13-valent vaccine in April 2010.
D. Thorrington   +4 more
semanticscholar   +1 more source

From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]

open access: yes, 2017
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core   +3 more sources

Origins of T‐cell‐mediated autoimmunity in acquired aplastic anaemia

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1035-1053, April 2025.
Acquired aplastic anaemia (AA) is an autoimmune bone marrow failure disease caused by a cytotoxic T‐cell–mediated attack on haematopoietic stem and progenitor cells (HSPCs). Despite significant progress in understanding T‐cell repertoire alterations in AA, the identification of specific pathogenic T cells remains elusive.
Aura Enache   +2 more
wiley   +1 more source

The alternative fact of probable vaccine damage A typology of vaccination beliefs in 28 European countries [PDF]

open access: yesarXiv, 2021
Background: Despite lacking scientific support, vaccine hesitancy is widespread. While vaccine damage as a scientific fact is statistically highly uncommon, emerging social and technological forces have converted probable vaccine damage into an alternative fact.
arxiv  

Public health impact of pneumococcal conjugate vaccine infant immunization programs: assessment of invasive pneumococcal disease burden and serotype distribution

open access: yesExpert Review of Vaccines, 2018
Introduction: Pneumococcal conjugate vaccine (PCV) impact studies have reported substantial reductions in the incidence of invasive pneumococcal disease (IPD) after implementation of childhood PCV programs.
P. Izurieta   +4 more
semanticscholar   +1 more source

Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response

open access: yesBMC Infectious Diseases, 2018
Background Community-acquired pneumonia is a leading infectious cause of hospitalization. A few vaccines exist to prevent pneumococcal disease in adults, including a pneumococcal polysaccharide unconjugated vaccine and a protein conjugated polysaccharide
Zhifeng Chen   +15 more
doaj   +1 more source

Analysis of pneumococcal serotypes distribution to determine a model composition for a Russian pneumococcal conjugate vaccine

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2022
Diseases caused by Streptococcus pneumoniae, as well as antibiotic resistance of its serotypes, are the leading cause of death amongst children worldwide.
V. P. Trukhin   +5 more
doaj   +1 more source

Preferences for COVID-19 vaccine: Evidence from India [PDF]

open access: yesarXiv, 2021
India's mass vaccination efforts have been slow due to high levels of vaccine hesitancy. This study uses data from an online discrete choice experiment with 1371 respondents to rigorously examine the factors shaping vaccine preference in the country. We find that vaccine efficacy, presence of side effects, protection duration, distance to vaccination ...
arxiv  

INTERNATIONAL EXPERIENCE WITH 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE

open access: yesПедиатрическая фармакология, 2009
The article is devoted to one of the serious problems of the today's medicine — pneumococcal infection. The authors show its importance for public health in terms of its influence upon infant and child mortality and in validization.
David G. McIntosh
doaj   +2 more sources

The role of the gut microbiota in regulating responses to vaccination: current knowledge and future directions

open access: yesThe FEBS Journal, Volume 292, Issue 6, Page 1480-1499, March 2025.
Vaccination plays a crucial role in mediating protection against infectious diseases, but immune responses to vaccination are highly variable and frequently sub‐optimal in vulnerable populations. Here, we review the latest preclinical and clinical evidence demonstrating that the gut microbiota plays a significant role in regulating immune responses to ...
Charné Rossouw   +2 more
wiley   +1 more source

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