Results 71 to 80 of about 46,971 (258)

Invasive Serotype 35B Pneumococci Including an Expanding Serotype Switch Lineage, United States, 2015–2016

Emerging Infectious Diseases, 2017
We used whole-genome sequencing to characterize 199 nonvaccine serotype 35B pneumococcal strains that caused invasive pneumococcal disease (IPD) in the United States during 2015–2016 and related these findings to previous serotype 35B IPD data obtained ...
Sopio Chochua, Benjamin J. Metcalf, Zhongya Li, Hollis Walker, Theresa Tran, Lesley McGee, Bernard Beall   +6 more
doaj   +1 more source

Aetiological Fraction of Influenza, Respiratory Syncytial Virus and Other Respiratory Pathogens in Infants Aged < 1 Year Hospitalised With Respiratory and Non‐Respiratory Medical Illness in South Africa, 2016–2018

Influenza and Other Respiratory Viruses, Volume 19, Issue 7, July 2025.
ABSTRACT Background Understanding the contribution of pathogens to respiratory illness in infants is important to guide interventions. We assessed the aetiology of respiratory pathogens among infants hospitalised with respiratory and non‐respiratory illness. Methods We conducted an unmatched case–control study among infants aged < 1 year.
Nicole Wolter, Cheryl Cohen, Anne von Gottberg, Stefano Tempia, Jocelyn Moyes, Claire von Mollendorf, Florette K. Treurnicht, Orienka Hellferscee, Kathleen Subramoney, Malefu Moleleki, Cayla Reddy, Lorens Maake, Mvuyo Makhasi, Neydis Baute, Sibongile Walaza   +14 more
wiley   +1 more source

Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000–2019: protocol for systematic review

BMJ Open, 2019
Introduction Africa harbours a high burden of pneumococcal disease, with associated high mortality rates. Despite 34 countries introducing the pneumococcal conjugate vaccine, which reduces the risk of pneumococcal carriage (a prerequisite for disease) of
Neil French, Dean Everett, Newton L. Kalata, Tinashe K. Nyazika, Todd D. Swarthout, Robert S. Heyderman, Stephen B. Gordon, Kondwani C. Jambo   +7 more
doaj   +1 more source

Increased carriage of non-vaccine serotypes with low invasive disease potential four years after switching to the 10-valent pneumococcal conjugate vaccine in The Netherlands

PLoS ONE, 2018
The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in The Netherlands in 2006 and was replaced by PHiD-CV10 in 2011. Data on carriage prevalence of S. pneumoniae serotypes in children and invasive pneumococcal disease (IPD) in children and
M. Vissers, A. Wijmenga-Monsuur, M. Knol, P. Badoux, M. V. van Houten, A. van der Ende, E. Sanders, N. Rots   +7 more
semanticscholar   +1 more source

Pneumococcal conjugate vaccine use in adults

Expert Review of Vaccines, 2015
Streptococcus pneumoniae is a leading cause of illness and death in adults. A polysaccharide vaccine has been available for over 30 years, but despite significant use, the public health impact of this vaccine has been limited. The 13-valent pneumococcal conjugate vaccine (PCV13) has been licensed by the US Food and Drug Administration and other ...
Raul E. Isturiz, Beate Schmoele-Thoma, Daniel A. Scott, Luis Jodar, Chris Webber, Heather L. Sings, Peter Paradiso   +6 more
openaire   +3 more sources

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

One year period of invasive pneumococcal disease in children from a tertiary care hospital in Turkey in the post-vaccine era

Human Vaccines & Immunotherapeutics, 2021
The incidence of invasive pneumococcal disease (IPD) has decreased after pneumococcal conjugate vaccine used; however, a breakthrough infection may still be seen after vaccination.
Gulnihan Ustundag, Eda Karadag-Oncel, Sebahat Sen-Tas, Ahu Kara-Aksay, Dilek Yilmaz-Ciftdogan, Nisel Yilmaz, Mehmet Ceyhan   +6 more
doaj   +1 more source

Invasive Pneumococcal Disease in Refugee Children, Germany

Emerging Infectious Diseases, 2018
Refugee children in Germany are not routinely given a pneumococcal conjugate vaccine. Cases of invasive pneumococcal disease (IPD) in 21 refugee children were compared with those in 405 Germany-born children for 3 pneumococcal seasons.
Stephanie Perniciaro, Matthias Imöhl, Mark van der Linden   +2 more
doaj   +1 more source

Prevention of Antibiotic-Nonsusceptible Invasive Pneumococcal Disease With the 13-Valent Pneumococcal Conjugate Vaccine.

Clinical Infectious Diseases, 2016
BACKGROUND Antibiotic-nonsusceptible invasive pneumococcal disease (IPD) decreased substantially after the US introduction of the pediatric 7-valent pneumococcal conjugate vaccine (PCV7) in 2000.
S. Tomczyk, R. Lynfield, W. Schaffner, A. Reingold, L. Miller, S. Petit, C. Holtzman, S. Zansky, A. Thomas, Joan Baumbach, L. Harrison, M. Farley, B. Beall, L. McGee, R. Gierke, Tracy Pondo, L. Kim   +16 more
semanticscholar   +1 more source

Safety and immunogenicity of 15-valent pneumococcal conjugate vaccine compared to 13-valent pneumococcal conjugate vaccine in adults ≥65 years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine

Human Vaccines & Immunotherapeutics, 2018
Background: Pneumococcal disease remains a public health priority in adults. Previous studies have suggested that administration of pneumococcal polysaccharide vaccine or pneumococcal conjugate vaccine within three years following receipt of PPV23 was ...
James T Peterson, Helen L Stacey, John Macnair, Jianing Li, J. Hartzel, T. Sterling, Patrice Benner, G. Tamms, L. Musey   +8 more
semanticscholar   +1 more source