IMMUNOGENICITY OF A PNEUMOCOCCAL PROTEIN CONJUGATE VACCINE IN INFANTS WITH SICKLE CELL DISEASE. ▴ 946 [PDF]
Katherine L. O’Brien+10 more
openalex +1 more source
Meta-analysis of Gene Expression in Neurodegenerative Diseases Reveals Patterns in GABA Synthesis and Heat Stress Pathways [PDF]
Neurodegenerative diseases are characterized as the progressive loss of neural cells, e.g. neurons, glial cells. Ageing, monogenic variations, viral infections, and many other factors are determined and speculated as causes for them. While many individual genes, such as APP for Alzheimer disease and HTT for Huntington disease, and biological pathways ...
arxiv
Serum Opsonic Activity for Streptococcus pneumoniae Types 6B and 14 in Infants with Sickle Cell Disease after Immunization with Pneumococcal Protein Conjugate Vaccine [PDF]
Anna Nowak‐Węgrzyn+4 more
openalex +1 more source
Global Authorship Representation in Otolaryngology Clinical Trials
The clinical trial literature in the four most widely circulated OHNS journals is dominated by HIC authorship, with only marginal growth in LMIC contributions and no representation from LICs over the past two decades. This underrepresentation may impact the applicability of clinical guidelines in lower‐income regions.
Hong‐Ho Yang+5 more
wiley +1 more source
Severe pneumococcal disease and temporary splenic dysfunction [PDF]
Michael Pelly+3 more
openalex +1 more source
Origins of T‐cell‐mediated autoimmunity in acquired aplastic anaemia
Acquired aplastic anaemia (AA) is an autoimmune bone marrow failure disease caused by a cytotoxic T‐cell–mediated attack on haematopoietic stem and progenitor cells (HSPCs). Despite significant progress in understanding T‐cell repertoire alterations in AA, the identification of specific pathogenic T cells remains elusive.
Aura Enache+2 more
wiley +1 more source
Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of ...
Ahmed H. Radhi+4 more
doaj
Snap and Diagnose: An Advanced Multimodal Retrieval System for Identifying Plant Diseases in the Wild [PDF]
Plant disease recognition is a critical task that ensures crop health and mitigates the damage caused by diseases. A handy tool that enables farmers to receive a diagnosis based on query pictures or the text description of suspicious plants is in high demand for initiating treatment before potential diseases spread further.
arxiv
Incidence of invasive pneumococcal disease and distribution of capsular types of pneumococci in Denmark, 1989–94 [PDF]
S. V. Nielsen, J Henrichsen
openalex +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review
Abstract In the past year, the European Medicines Agency (EMA), the Food and Drug Administration (FDA) and the Medicines and Healthcare Products Regulatory Agency (MHRA) authorised 53 novel drugs. While the 2024 harvest is not as rich as in 2023, when 70 new chemical entities were approved, the number of ‘orphan’ drug authorisations in 2024 (21) is ...
Stavros Topouzis+16 more
wiley +1 more source