Results 121 to 130 of about 3,296,751 (334)

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 4, Issue 11, November 2025.
ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellular communication, exceeding the simplistic interactions observed with individual molecules. In this comprehensive
Philipp Arnold, Fanni Annamária Boros, Jochen Mattner, Gerald Seidel, Chaofan Liu, Inga Viktoria Hensel, Jan Van Deun, Raphael Schwendner, Janina Müller‐Deile, Nina Sopel, Andreas Ramming, Mario R. Angeli, Simon Rauber, Cláudia Vilhena, Andreas Baur, Stefan Wirtz, Klaus Überla, Heiko Reutter, Linda‐Marie Mulzer, Alina C. Hilger, Friederike Zunke, Wei Xiang, Gregor Fuhrmann, Claudia Günther   +23 more
wiley   +1 more source

B-VITAMIN AND PNEUMOCOCCAL INFECTION [PDF]

, 1922
G. M. Findlay
openalex   +1 more source

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

Acta Paediatrica, Volume 114, Issue 11, Page 2993-2999, November 2025.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä, Kaarina Kukkonen, Svetlana Vakkilainen   +2 more
wiley   +1 more source

Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management. [PDF]

, 2019
Community-acquired pneumonia (CAP) is a common cause of pediatric hospital admission. Empiric antibiotic therapy for hospitalized children with serious CAP now targets the most likely pathogen(s), including those that may demonstrate significant ...
Bradley, John S, Cannavino, Christopher R, Coufal, Nicole G, Farnaes, Lauge, Foley, Jennifer, Hong, David K, Pong, Alice, Ryan Loker, Kathleen, Wilke, Julianne   +8 more
core  

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Pneumococcal infections in children with sickle cell disease before and after pneumococcal conjugate vaccines. [PDF]

Blood Adv, 2023
Adamkiewicz TV, Yee MEM, Thomas S, Tunali A, Lai KW, Omole FS, Lane PA, Yildirim I.   +7 more
europepmc   +1 more source

Systemic treatment of immune checkpoint inhibitor‐induced psoriasis: Inference‐based guidance

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 11, Page 1881-1894, November 2025.
When managing psoriasis, induced or exacerbated by ICI therapy for cancer, there are concerns regarding immunosuppression from systemic agents for the treatment of psoriasis and the potential impact on ICI efficacy. No direct, high‐level evidence exists to address these concerns.
Kim A. Papp, Luis Puig, Jennifer Beecker, Vinod Chandran, Joël Claveau, Javier Cortés, Jan Dutz, Noah I. Hornick, Rosalyn A. Juergens, Barbara Melosky, Anisha B. Patel, Maxwell B. Sauder, Sandeep Sehdev, Vincent Sibaud, Stephanie L. Snow   +14 more
wiley   +1 more source

Pneumolysin as a target for new therapies against pneumococcal infections: A systematic review. [PDF]

PLoS One, 2023
Cima Cabal MD, Molina F, López-Sánchez JI, Pérez-Santín E, Del Mar García-Suárez M.   +4 more
europepmc   +1 more source

The Effect of Alcoholic Intoxication Upon Acquired Resistance to Pneumococcal Infection in Rabbits [PDF]

, 1943
C. C. Lushbaugh
openalex   +1 more source

Wandering Spleen, A Rare Cause of Acute Abdomen: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT A wandering spleen (WS) is rare and often presents a diagnostic challenge to clinicians. We report a WS in a 16‐year‐old who presented with abdominal pain, vomiting, and peritonism. Imaging (ultrasound and CT scans), which usually facilitates a prompt diagnosis, was inconclusive, and the diagnosis was made by exploratory laparotomy.
John Kanyiri Yambah, Kojo Amanfo Ninson, Abdul Samed Sulemana, Richardson Edwin Annan, Vishnu Nene Limon Abayateye, Gifty Aba Donkor, Moses Dokurugu, Ninnang Tobias   +7 more
wiley   +1 more source