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Pediatrics In Review, 2014
Overwhelmingly consistent evidence from observational studies has demonstrated that the pneumococcal conjugate vaccine has reduced the burden of pneumococcal disease but continues to affect the epidemiology of pneumococcal infections caused by nonvaccine serotypes and antibiotic-resistant pneumococci.
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Overwhelmingly consistent evidence from observational studies has demonstrated that the pneumococcal conjugate vaccine has reduced the burden of pneumococcal disease but continues to affect the epidemiology of pneumococcal infections caused by nonvaccine serotypes and antibiotic-resistant pneumococci.
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Pathogenesis of Pneumococcal Infection
New England Journal of Medicine, 1995The study of Streptococcus pneumoniae has led to many insights into the pathogenesis of bacterial infections. The importance of the polysaccharide capsule of the organism in determining its virulence was indicated by studies of the protective role of anticapsular antibodies.1–3 Of comparable importance was the observation that noncapsulated pneumococci
E I, Tuomanen, R, Austrian, H R, Masure
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Pneumococcal Infection and Pneumococcal Vaccine
New England Journal of Medicine, 1977The pneumococcus (Streptococcus pneumoniae) is a major cause of pneumonia, otitis media and meningitis throughout the world. Although the mortality resulting from pneumococcal infection has declined strikingly since the introduction of the sulfonamides, penicillin and other antibiotics, what limited epidemiologic evidence is available suggests that the
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Pneumococcal Infections and Pneumococcal Vaccine: An Update
Infection Control, 1982AbstractPneumococcal pneumonia continues to be an important disease in terms of prevalence, morbidity and mortality. With the discovery of penicillin and its wide clinical use, the overall mortality of pneumococcal pneumonia has been significantly reduced, but problems remain.
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Pharmacotherapy for pneumococcal infections: an update
Expert Opinion on Pharmacotherapy, 2012The management of pneumococcal diseases still places a significant burden on medical and economic resources. The subjects at greatest risk of pneumococcal infections are children.The aim of this review is to analyse the best current therapeutic approach to pneumococcal resistance, taking into account the level of susceptibility of Streptococcus ...
S. Esposito, N. Principi
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Minerva medica, 1983
Current knowledge of the morphology, biochemistry and function of streptococcus Pneumoniae, the immune response of the host to infection and certain epidemiological aspects of pneumococcus infections is described. Personal experience of acute infections of the lower respiratory ways and meninges is presented and therapeutic problems are discussed.
F, Di Nola, M L, Soranzo
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Current knowledge of the morphology, biochemistry and function of streptococcus Pneumoniae, the immune response of the host to infection and certain epidemiological aspects of pneumococcus infections is described. Personal experience of acute infections of the lower respiratory ways and meninges is presented and therapeutic problems are discussed.
F, Di Nola, M L, Soranzo
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Current Opinion in Infectious Diseases, 1997
Keith P. Klugman, Charles Feldman
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Keith P. Klugman, Charles Feldman
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2010
Streptococcus pneumoniae is an encapsulated Gram-positive bacterium that lives almost exclusively in the human nasopharynx. Each pneumococcus expresses one of more than 90 immunologically distinguishable capsular polysaccharides that are the principal target of systemic human immunity and define its serotype ...
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Streptococcus pneumoniae is an encapsulated Gram-positive bacterium that lives almost exclusively in the human nasopharynx. Each pneumococcus expresses one of more than 90 immunologically distinguishable capsular polysaccharides that are the principal target of systemic human immunity and define its serotype ...
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