Results 71 to 80 of about 42,790 (192)

Sutimlimab in Patients With Cold Agglutinin Disease (CAD): Results From a Managed Access Program

European Journal of Haematology, Volume 116, Issue 4, Page 409-415, April 2026.
ABSTRACT Cold agglutinin disease (CAD) is a low‐grade lymphoproliferative disorder accounting for 15%–30% of patients suffering from autoimmune hemolytic anemias. The clonal B cells produce autoantibodies primarily of the IgM‐κ class that cause agglutination of red blood cells (RBCs) at temperatures ≤ 37°C and activate the classical complement pathway ...
Sandra Maria Frey, Pauline Halberstadt, Ferras Alashkar, Veronika Lenz, H. Christian Reinhardt, Alexander Röth   +5 more
wiley   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, Volume 116, Issue 4, Page 336-349, April 2026.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

Risdiplam Impact in Treatment Naïve and Non‐Naïve Pediatric and Adult Patients With Spinal Muscular Atrophy

European Journal of Neurology, Volume 33, Issue 4, April 2026.
This 36‐month prospective study of 34 symptomatic SMA patients (ages 6.9–50.9 years) found significant motor and quality of life improvements with risdiplam treatment. Treatment‐naïve patients showed notable gains in MFM‐32 and RULM scores, while those switching therapies improved in MFM‐32.
Pak On Patrick Yee, Hayley Hoi Ning Ip, Michael Kwan Leung Yu, Pui Kei Cheng, Wilfred Hing Sang Wong, Patrick Pak Hei Ng, Nathan Sheung Tat Kwong, Priscillia Lam, Mei Wun Cheung, Angel Tung, Stephen Chan, Shirley Ng, Wai Lan Yeung, Sheila Wong, Yuen Gao, Shirley Pang, Sophelia Hoi Shan Chan   +16 more
wiley   +1 more source

Pneumococcal vaccination and chronic respiratory diseases

International Journal of COPD, 2017
Filipe Froes,1 Nicolas Roche,2 Francesco Blasi3,4 1Chest Department, Hospital Pulido Valente, North Lisbon Hospital Center, Lisbon, Portugal; 2Department of Respiratory and Intensive Care Medicine, Cochin Hospital, Paris Descartes University, Paris ...
Froes F, Roche N, Blasi F
doaj  

Preventing First and Further Decompensation in Advanced Chronic Liver Disease

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Advanced chronic liver disease (ACLD) remains a major cause of global morbidity and mortality. Preventing hepatic decompensation—both the first event and subsequent recurrences—has become a central therapeutic goal to prolong survival. The transition from the compensated phase (cACLD) to the decompensated phase (dACLD) is driven by clinically ...
Leonardo Corrêa Süffert, Bernardo de Faria Moraes, Guilherme Grossi Lopes Cançado   +2 more
wiley   +1 more source

Epidemiology of S. pneumoniae serotypes in the Russian Federation [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
The prevalence of the common serotypes of S. pneumoniae in the Russian Federation was estimated in healthy carriers as well as children and adult patients with invasive and non-invasive pneumococcal infections based on the epidemiological microbiological
Muravyev A.A., Kozlov R.S., Lebedeva N.N.   +2 more
doaj  

Pneumococcal infections in children with sickle cell disease before and after pneumococcal conjugate vaccines. [PDF]

Blood Adv, 2023
Adamkiewicz TV, Yee MEM, Thomas S, Tunali A, Lai KW, Omole FS, Lane PA, Yildirim I.   +7 more
europepmc   +1 more source

Pneumolysin as a target for new therapies against pneumococcal infections: A systematic review. [PDF]

PLoS One, 2023
Cima Cabal MD, Molina F, López-Sánchez JI, Pérez-Santín E, Del Mar García-Suárez M.   +4 more
europepmc   +1 more source

Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia

Journal of Infection and Public Health
Background: People living with HIV (PLWH) are recognized as a high-risk population for opportunistic infections, including community-acquired pneumonia (CAP).
Reem Binsuwaidan, Enas Mosaffer Alghamdi, Ethar Abdullhameed Otaif, Maram Saud ALqutaym, Yahya Ali Mohzari, Ahmed Ali Alrashed, Rowdan Zeyan Alderaan, Ahmed Ajlan Alsheheri, Alaa Alhubaishi, Lina I Alnajjar   +9 more
doaj   +1 more source

Pneumococcal nasopharyngeal carriage in children and adults self-confined at home during a COVID-19 national lockdown.

PLoS ONE
BackgroundDespite growing evidence of reduced invasive and non-invasive pneumococcal disease attributed to public health measures against the COVID-19 pandemic, the effect of these measures on pneumococcal carriage remains unclear.
Pedro Brotons, María Cisneros, Amaresh Pérez-Argüello, Desiree Henares, Aleix Lluansí, Mariona Fernández de Sevilla, Pilar Ciruela, Miguel Blanco-Fuertes, Cristian Launes, Iolanda Jordan, Quique Bassat, Juan José García-García, Carmen Muñoz-Almagro   +12 more
doaj   +1 more source