Results 51 to 60 of about 20,003 (217)

Pneumococcal meningitis in Iran: a systematic review and meta–analysis

open access: yesJournal of Acute Disease, 2019
Objective: To estimate the frequency of pneumococcal meningitis among patients with bacterial meningitis in Iran. Methods: PubMed, Embase, Web of Science and Scientific Information Database (www.sid.ir) were searched from 2000 to 2016 to identify studies
Sedigheh Rafiei Tabatabaei   +5 more
doaj   +1 more source

Burden of pneumococcal disease in children in Cuba before the introduction of a novel pneumococcal conjugate vaccine

open access: yesJournal of Global Health Reports, 2019
# Background The Cuban heptavalent conjugate pneumococcal vaccine will be introduced for children beginning in 2020. We estimated the burden of pneumococcal cases and deaths in children 1-59 months in 2015.
Nivaldo Linares-Pérez   +4 more
doaj   +1 more source

Development of a Clinical Severity Score for Indian Sickle Cell Anaemia Patients

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Sickle cell anaemia (SCA) is a monogenic disorder but shows variable disease severity. We evaluated the utility of paediatric severity scores (PSS) in Indian patients and developed two modified scores: Indian Severity Score 1 (ISS1) by adding four clinical parameters to PSS, and ISS2 by excluding four biochemical measures from ISS1.
Suraj S. Nongmaithem   +6 more
wiley   +1 more source

Estudi experimental del tractament de la meningitis pneumocòcica produïda per soques resistents a cefalosporines de tercera generació. Virulència, eficàcia i resposta inflamatòria [PDF]

open access: yes, 2006
[cat] La meningitis pneumocòcica és una malaltia associada a una elevada mortalitat (20-40) i a l'aparició de seqüeles neurològiques en un 30% dels pacients, nens i adults, que sobreviuen.
Ribes Miravet, Sandra
core  

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

open access: yesClinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson   +12 more
wiley   +1 more source

Correlation between CSF Glucose Level and Outcome on Adult Patients with Meningitis [PDF]

open access: yes, 2008
Background: Meningitis is an inflammatory response to infection of leptomeningeal cells and subarachnoid space. The severity of the inflammation could be reflected on the CSF glucose level.
Sari, Pramita
core  

Brain levels of neuropeptide Y in experimental pneumococcal meningitis [PDF]

open access: yes, 1993
Neuropeptide Y (NPY), which is found in high concentrations in several regions of the brain including nuclei of the brain stem and in nerve fibers surrounding cerebral vessels, has been proposed to play a role in regulating cerebral blood flow (CBF) and ...
Täuber, MG   +4 more
core   +1 more source

Dynamic models of pneumococcal carriage and the impact of the Heptavalent Pneumococcal Conjugate Vaccine on invasive pneumococcal disease. [PDF]

open access: yes, 2010
BACKGROUND: The 7-valent pneumococcal conjugate vaccine has been introduced in national immunisation programmes of most industrialised countries and recently in two African GAVI eligible countries (Rwanda and The Gambia). However the long term effects of
George, Robert   +18 more
core   +1 more source

Retrospective database analysis for clinical diagnoses commonly associated with pneumococcal diseases in the Malaysian healthcare system over a 3-year period (2013–2015)

open access: yesBMC Infectious Diseases
Background Pneumococcal disease caused by Streptococcus pneumoniae is an important cause of morbidity and mortality across all ages, particularly in younger children and older adults. Here, we describe pneumococcal disease hospitalizations at Ministry of
Saravanan S. R. Sundaramurthy   +9 more
doaj   +1 more source

Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome

open access: yesEBioMedicine, 2016
Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Early recognition of the pathogen and subsequent innate immune response play a vital role in disease susceptibility and outcome. Genetic variations in innate immune genes
Bart Ferwerda   +8 more
doaj   +1 more source

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