Results 101 to 110 of about 30,753 (249)

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia

Molecular Medicine, 2019
Background Streptococcus pneumoniae is a major causative agent in community-acquired pneumonia and sepsis. Overwhelming lung inflammation during pneumococcal pneumonia may hamper lung function.
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos   +7 more
doaj   +1 more source

Impact of pneumococcal conjugate vaccination: a retrospective study of hospitalization for pneumonia in North-East Italy [PDF]

, 2016
Introduction. Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. Methods. All
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Buja, Alessandra, Clagnan, E, Cocchio, Silvia, Del Zotto, S, Furlan, Patrizia, Gallo, T, Saia, Mario   +9 more
core   +1 more source

Beyond Childhood: Adult and Adolescent Sickle Cell Disease and Outcomes in Northern Ghana

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Background Adults and adolescents face different barriers to healthcare utilization compared to children. Objective To describe adult and adolescent sickle cell disease (SCD) and outcomes in northern Ghana. Methods This was a retrospective cohort study of SCD patients aged 13 years and above, admitted between January 1, 2021 and December 31 ...
Kwadwo Faka Gyan, Solomon Gyabaah, Eunice Agyeman Ahmed, Lesley Osei, Mohammed Najeeb Naabo, Michael Asiedu Owiredu, Yaw Obeng Opare‐Addo, Jessey Mahama Holu, Ohene Kwaku Opare‐Sem   +8 more
wiley   +1 more source

Occult pneumococcal septicemia and pneumococcal pneumonia complicating pneumatoceles in a previously healthy child

The Turkish Journal of Pediatrics, 1998
Fulminating pneumococcal septicemia without an obvious focus of infection is very rare in previously immunocompetent children older than two years. Furthermore, pneumatocele formation in pneumococcal pneumonia is uncommon.
Y Aslan, F Orhan, H Dinç, H Soylu, E Erduran   +4 more
doaj  

Serotypes and antibiotic susceptibility of isolated from hospitalized patients with community-acquired pneumonia in Italy

SAGE Open Medicine, 2017
Background: Pneumonia remain an important public health problem. The primary objective was to determine the proportion of community-acquired pneumonia that is attributable to Streptococcus pneumoniae infection; secondary objectives were the description ...
Marta Di Pasquale, Stefano Aliberti, Chara Azzari, Maria Moriondo, Francesco Nieddu, Francesco Blasi, Marco Mantero   +6 more
doaj   +1 more source

Neonatal meningitis caused by streptococcus pneumonia in Iran [PDF]

, 2015
Meningitis, pneumonia, and sepsis in newborns and young infants ...
Alaee, E., Bakhtiari, M., Shaye, M.A., Shaye, Z.A.   +3 more
core  

Targeted Therapies for Rheumatoid Arthritis in Super‐Elderly Society: Insights From FIRST Registry, Japan

International Journal of Rheumatic Diseases, Volume 28, Issue 4, April 2025.
ABSTRACT As the world's most rapidly aging society, Japan has faced significant challenges in the management of rheumatoid arthritis (RA) in elderly patients. Biologic and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) have improved disease control, but concerns remain regarding the risk of infection and malignancy, especially in
Koshiro Sonomoto, Yoshiya Tanaka
wiley   +1 more source

Proposing a two-step Decision Support System (TPIS) based on Stacked ensemble classifier for early and low cost (step-1) and final (step-2) differential diagnosis of Mycobacterium Tuberculosis from non-tuberculosis Pneumonia [PDF]

arXiv, 2020
Background: Mycobacterium Tuberculosis (TB) is an infectious bacterial disease presenting similar symptoms to pneumonia; therefore, differentiating between TB and pneumonia is challenging. Therefore, the main aim of this study is proposing an automatic method for differential diagnosis of TB from Pneumonia.
arxiv  

Estimating the transmission parameters of pneumococcal carriage in households [PDF]

, 2004
This paper analyses Streptococcus pneumoniae transmission dynamics in households using longitudinal data on pneumococcal (Pnc) carriage in the United Kingdom. Ten consecutive swabs were taken at 4-week intervals from all members of 121 households.
Gay, N. J., Medley, Graham, Melegaro, Alessia   +2 more
core   +2 more sources

Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data.

PLoS Medicine, 2015
BackgroundThe importance of bacterial infections following respiratory syncytial virus (RSV) remains unclear. We evaluated whether variations in RSV epidemic timing and magnitude are associated with variations in pneumococcal disease epidemics and ...
Daniel M Weinberger, Keith P Klugman, Claudia A Steiner, Lone Simonsen, Cécile Viboud   +4 more
doaj   +1 more source