Results 51 to 60 of about 29,361 (134)

Sex Differences in Lung Immunity

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Biological sex has a significant impact on how the immune system develops and responds to foreign and self‐antigens. Sex differences exist in innate and adaptive immune cells, both at homeostasis and in the context of infection and inflammatory diseases such as asthma, cancer, and autoimmune disorders.
Franz Puttur, Clare M. Lloyd
wiley   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 636-647, March 2026.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui, Marnie Bertolet, Daniel E. Forman, Michelle E. Danielson, Shanshan Yao, Oscar L. Lopez, Nancy W. Glynn, Neelesh K. Nadkarni, Akira Sekikawa, Tullia C. Bruno, Toren Finkel, Anne B. Newman   +11 more
wiley   +1 more source

Occult pneumococcal septicemia and pneumococcal pneumonia complicating pneumatoceles in a previously healthy child

The Turkish Journal of Pediatrics, 1998
Fulminating pneumococcal septicemia without an obvious focus of infection is very rare in previously immunocompetent children older than two years. Furthermore, pneumatocele formation in pneumococcal pneumonia is uncommon.
Y Aslan, F Orhan, H Dinç, H Soylu, E Erduran   +4 more
doaj  

Prevalence of pneumococcal carriage and risk factors for pneumonia and carriage among under-5 children in Malaysia: findings from the MY-Pneumo study

Pneumonia
Background Paediatric pneumonia remains a significant public health concern globally, and the risk factors for pneumonia and carriage vary across different populations. The accuracy of pneumococcal urinary antigen test (PUAT) remains unclear. We aimed to
Hoomashini Gunasegaran, Nurul Hanis Ramzi, Andrew Chun Hoong Tan, Nur Alia Johari, Anna Marie Nathan, Norhayati Aida Sulaiman, Cindy Shuan Ju Teh, Mohamad Ikram Ilias, Zakuan Zainy Deris, Siti Nur Haidar Hazlan, Nur Syafiqah Mohamad Nasir, Asrar Abu Bakar, Muhd Alwi Muhd Helmi, Wan Khairunnisa Wan Juhari, Norhidayah Kamarudin, Chun Wie Chong, David W. Cleary, Stuart C. Clarke, Lokman Hakim Sulaiman   +18 more
doaj   +1 more source

Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data.

PLoS Medicine, 2015
BackgroundThe importance of bacterial infections following respiratory syncytial virus (RSV) remains unclear. We evaluated whether variations in RSV epidemic timing and magnitude are associated with variations in pneumococcal disease epidemics and ...
Daniel M Weinberger, Keith P Klugman, Claudia A Steiner, Lone Simonsen, Cécile Viboud   +4 more
doaj   +1 more source

Are the pneumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials

BMC Family Practice, 2000
The objective was to review the evidence of effectiveness of the polyvalent polysaccharide pneumococcal vaccine from prospective properly randomised controlled trials comparing pneumococcal vaccines with placebo in subjects who are immunocompetent and ...
Lipsky Benjamin A, Wiffen Philip J, Moore R Andrew   +2 more
doaj   +1 more source

Burden of Pneumococcal Disease in Northern Togo before the Introduction of Pneumococcal Conjugate Vaccine.

PLoS ONE, 2017
BackgroundS. pneumoniae is a leading cause of meningitis morbidity and mortality in the African meningitis belt, but little is known of its contribution to the burden of pneumonia in the region.
Jennifer C Moïsi, Makawa-Sy Makawa, Haoua Tall, Kodjo Agbenoko, Berthe-Marie Njanpop-Lafourcade, Stanislas Tamekloe, Moussa Amidou, Judith E Mueller, Bradford D Gessner   +8 more
doaj   +1 more source

Serotypes and antibiotic susceptibility of isolated from hospitalized patients with community-acquired pneumonia in Italy

SAGE Open Medicine, 2017
Background: Pneumonia remain an important public health problem. The primary objective was to determine the proportion of community-acquired pneumonia that is attributable to Streptococcus pneumoniae infection; secondary objectives were the description ...
Marta Di Pasquale, Stefano Aliberti, Chara Azzari, Maria Moriondo, Francesco Nieddu, Francesco Blasi, Marco Mantero   +6 more
doaj   +1 more source

Efficacy of conjugate vaccines in pneumococcal infection prevention

Журнал инфектологии, 2014
The problem of pneumococcal infection is actual for many countries of the world in connection with high incidence and mortality. Vaccination by the 7-valent conjugated pneumococcal vaccine of children till 2 years is available in Russia since 2009, 13 ...
A. L. Perova, A. V. Rudakova, S. M. Kharit   +2 more
doaj   +1 more source

The efficacy of high-dose penicillin G for pneumococcal pneumonia diagnosed based on initial comprehensive assessment at admission: an observational study

BMC Research Notes, 2018
Objectives High-dose penicillin therapy is effective in approximately 90% of pneumococcal pneumonia cases diagnosed based on urinary pneumococcal antigen tests or Gram staining at admission.
Junpei Komagamine
doaj   +1 more source