Results 61 to 70 of about 37,942 (184)

HIV: is it now a thing of the past?

Internal Medicine Journal, EarlyView.
Abstract Effective antiviral therapy for human immunodeficiency virus (HIV) has substantially reduced HIV‐associated morbidity and mortality for people living with HIV (PLWH). The use of antiviral therapies as prevention, most notably pre‐exposure prophylaxis (PrEP) as well as treatment as prevention (TasP), has significantly reduced the number of new ...
Jeffrey John Post
wiley   +1 more source

PNEUMOCOCCAL INFECTION — IN THE CENTRE OF ATTENTION AGAIN

Вопросы современной педиатрии, 2009
This article present a general review on pneumococcal infection, its prevalence, clinic types in children in Russia and worldwide. Description of S. pneumoniae serotypes' distribution and its influence at clinical manifestation of pneumococcal infection ...
S.V. Sidorenko
doaj   +2 more sources

PNEUMOCOCCAL INFECTION. IMMUNIZATION BY A 7-VALENT CONJUGATED PNEUMOCOCCAL VACCINE OF CHILDREN BORN TO HIV-POSITIVE WOMEN

Вопросы современной педиатрии, 2011
The article contains pneumococcal infection prevalence survey among HIV-positive children. Questions of pneumococcal infection prevention using pneumococcal conjugated vaccine are discussed in the article.
L.Yu Afoninа, E.E. Voronin, Yu.A. Fomin, Yu.V. Lobzin   +3 more
doaj  

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 4, Issue 11, November 2025.
ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellular communication, exceeding the simplistic interactions observed with individual molecules. In this comprehensive
Philipp Arnold, Fanni Annamária Boros, Jochen Mattner, Gerald Seidel, Chaofan Liu, Inga Viktoria Hensel, Jan Van Deun, Raphael Schwendner, Janina Müller‐Deile, Nina Sopel, Andreas Ramming, Mario R. Angeli, Simon Rauber, Cláudia Vilhena, Andreas Baur, Stefan Wirtz, Klaus Überla, Heiko Reutter, Linda‐Marie Mulzer, Alina C. Hilger, Friederike Zunke, Wei Xiang, Gregor Fuhrmann, Claudia Günther   +23 more
wiley   +1 more source

The direct and indirect effects of the pneumococcal conjugated vaccine on carriage rates in children aged younger than 5 years in Latin America and the Caribbean: a systematic review

Einstein (São Paulo)
Objective To demonstrate the impact of pneumococcal conjugate vaccine in Streptococcus pneumoniae carriage status in children younger than 5 years in Latin America and the Caribbean. Methods A systematic literature review was carried out on the direct
Stefany Martins Silva, Izabella Caroline Gebrim Rodrigues, Rodrigo da Silva Santos, Yves Mauro Fernandes Ternes   +3 more
doaj   +2 more sources

Antibiotic Resistance: A Genetic and Physiological Perspective

MedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy, Ahmed H. El‐Sappah, Rong Guo, Xiaoling Luo, Shiyuan Deng, Meifang Du, Xiaohong Jian, Mohammed Bakeer, Zaixin Li, Zhi Zhang   +9 more
wiley   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

The Cost-Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine in Seven Chinese Cities [PDF]

, 2021
Yan Li, Huaqing Wang, Wesley Furnback, Bruce C. M. Wang, Shuiqing Zhu, Peng Dong   +5 more
openalex   +1 more source

Oral Microbiota Linking Humoral Response, Periodontitis and Atherosclerosis

Journal of Clinical Periodontology, Volume 52, Issue 11, Page 1550-1559, November 2025.
ABSTRACT Aim The humoral immune system is implicated in the link between periodontitis and atherosclerosis. This study aims to explore how interactions between the oral microbiota and humoral immune responses may contribute to this association. Materials and Methods We analysed data from the Northern Finland Birth Cohort 1966, which included 1560 ...
Ramin Akhi, Anton Lavrinienko, Miia Hakula, Rasmus Hindström, Chunguang Wang, Antti Nissinen, Arja M. Kullaa, Tuula Salo, Kari Kaikkonen, Tellervo Tervonen, Pekka Ylöstalo, Janne J. Koskimäki, Sohvi Hörkkö   +12 more
wiley   +1 more source