Proposal of a Vaccination Needs Index to Prioritise Municipal Interventions in Brazil
ABSTRACT Addressing population health needs requires integrating indicators expressed on non‐comparable scales, particularly for vaccination, a cornerstone of public health. Objective To propose and implement a Vaccination Needs Index based on national administrative data on tracer vaccines for children to support the prioritisation of Brazilian ...
Fredi Alexander Diaz‐Quijano +4 more
wiley +1 more source
Low Baseline Pneumococcal Antibody Titers Predict Specific Antibody Deficiency, Increased Upper Respiratory Infections, and Allergy Sensitization. [PDF]
Background:Inadequate titers of pneumococcal antibody (PA) are commonly present among patients with recurrent respiratory infections. Objective:We sought to determine the effect of the degree of inadequacy in baseline PA titers on the subsequent ...
Chernikova, Diana +5 more
core
Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino +10 more
wiley +1 more source
Shingles & Pneumococcal Vaccines: Recommendations for Older Adults [PDF]
As the immune system tends to weaken over time, patients aged 50+ begin having increased risk for certain potentially preventable diseases, especially shingles and pneumonia.
Flinn, Benjamin
core +1 more source
Abstract HPV vaccination reduces the risk of developing HPV‐attributable cancers, including cervical cancer. However, an attenuation of HPV vaccine impact after the implementation of HPV vaccination may occur through clinical unmasking. Clinical unmasking is a distinct and complex phenomenon that arises in the absence of clinical interventions ...
Joseph E. Tota +8 more
wiley +1 more source
Objective To demonstrate the impact of pneumococcal conjugate vaccine in Streptococcus pneumoniae carriage status in children younger than 5 years in Latin America and the Caribbean. Methods A systematic literature review was carried out on the direct
Stefany Martins Silva +3 more
doaj +2 more sources
Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California [PDF]
We sought to identify the characteristics of men who have sex with men (MSM) who are opinion leaders on immunization issues and to identify potential opportunities to leverage their influence for vaccine promotion within MSM communities.
Bednarczyk, Robert +9 more
core +3 more sources
ABSTRACT There is limited information regarding the contemporary real‐world clinical and financial burden of Medicaid enrollees with sickle cell disease (SCD) in the United States. Using the IBM MarketScan Medicaid database (7/2016–12/2020), individuals with ≥ 3 SCD diagnoses were matched 1:1 on age, gender, and race to individuals without SCD ...
Giovanna Tedesco Barcelos +4 more
wiley +1 more source
Impact of pneumococcal conjugate vaccination: a retrospective study of hospitalization for pneumonia in North-East Italy [PDF]
Introduction. Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. Methods. All
Baldo, Vincenzo +9 more
core +1 more source
Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
AD Reynolds +62 more
core +3 more sources

