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Pediatric Clinics of North America, 2000
Streptococcus pneumoniae or pneumococcus is a major pathogen causing meningitis, pneumonia, other invasive infections, and the common infections acute otitis media and sinusitis. The major virulence factor is the polysaccharide capsule, present as one of approximately 90 serotypes. Anticapsular antibodies protect against infection.
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Streptococcus pneumoniae or pneumococcus is a major pathogen causing meningitis, pneumonia, other invasive infections, and the common infections acute otitis media and sinusitis. The major virulence factor is the polysaccharide capsule, present as one of approximately 90 serotypes. Anticapsular antibodies protect against infection.
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Nursing Clinics of North America
Pneumococci are the most common bacterial cause of childhood pneumonia, especially in children aged younger than 5 years. In adults, pneumococci account for 10% to 30% of adult community-acquired pneumonia. The conjugate pneumococcal vaccines have been shown to have a remarkable effect, reducing the incidence of all types of pneumococcal diseases ...
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Pneumococci are the most common bacterial cause of childhood pneumonia, especially in children aged younger than 5 years. In adults, pneumococci account for 10% to 30% of adult community-acquired pneumonia. The conjugate pneumococcal vaccines have been shown to have a remarkable effect, reducing the incidence of all types of pneumococcal diseases ...
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Pneumococcal Infection and Pneumococcal Vaccine
New England Journal of Medicine, 1977The pneumococcus (Streptococcus pneumoniae) is a major cause of pneumonia, otitis media and meningitis throughout the world. Although the mortality resulting from pneumococcal infection has declined strikingly since the introduction of the sulfonamides, penicillin and other antibiotics, what limited epidemiologic evidence is available suggests that the
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Pneumococcal Infections and Pneumococcal Vaccine: An Update
Infection Control, 1982AbstractPneumococcal pneumonia continues to be an important disease in terms of prevalence, morbidity and mortality. With the discovery of penicillin and its wide clinical use, the overall mortality of pneumococcal pneumonia has been significantly reduced, but problems remain.
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Correction: Pneumococcal Vaccine and Pneumococcal Pneumonia
Annals of Internal Medicine, 1988Excerpt To the Editor:Sims and colleagues made the following statement in their article on pneumococcal vaccine (1): Studies of sufficient statistical power have consistently shown the efficacy of ...
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Pneumococcal vaccination of children
Seminars in Pediatric Infectious Diseases, 2002Streptococcus pneumoniae is the most frequent cause of invasive bacterial infection in children younger than 2 years of age, reaching a peak incidence at 6 to 12 months of age. Pneumococci also cause many cases of pneumonia, sinusitis, and otitis media.
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Annals of Internal Medicine, 1986
Excerpt To the editor: In the January issue, Bolan and colleagues (1) describe their analysis of the distribution of pneumococcal serotypes isolated from blood and cerebrospinal fluid of vaccinated...
M, Aloizou, S, Lomasky, P D, Lief
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Excerpt To the editor: In the January issue, Bolan and colleagues (1) describe their analysis of the distribution of pneumococcal serotypes isolated from blood and cerebrospinal fluid of vaccinated...
M, Aloizou, S, Lomasky, P D, Lief
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Pneumococcal conjugate vaccine
Current Opinion in Pediatrics, 2001Pneumococcal infections account for a significant proportion of bacterial infections in infants and children. The growing threat from pneumococci resistant to penicillin and other antimicrobials has led to increased pressure for the development of an effective vaccine.
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Pneumococcal conjugate vaccines
Immunology Letters, 1991We have prepared conjugates of pneumococcal type 4 polysaccharides (PS4) or oligosaccharides to tetanus toxoid using the carbodiimide method. The use of a spacer, 6-aminohexanoic acid, resulted in higher incorporation of carrier protein. Conjugates contained up to 10% free polysaccharide, but no free protein.
C C, Peeters +6 more
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Pneumococcal Vaccine: An Update
Pediatrics, 1999* Abbreviation: HIV = : human immunodeficiency virus Streptococcus pneumoniae is the most common cause of invasive bacterial infection in children. In addition, the organism causes 30% to 50% of cases of acute otitis media; 24 million visits to pediatricians per year in the United States are referable to this diagnosis.1 It is also ...
R P, Wadwa, R D, Feigin
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