Results 91 to 100 of about 51,262 (290)

National case-control study of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men: Part 1. Epidemiologic results.

Annals of Internal Medicine, 1983
To identify risk factors for the occurrence of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men, we conducted a case-control study in New York City, San Francisco, Los Angeles, and Atlanta.
H. Jaffe, K. Choi, P. Thomas, H. Haverkos, D. Auerbach, M. Guinan, M. Rogers, T. Spira, W. Darrow, M. Kramer, S. Friedman, J. Monroe, A. Friedman-kien, L. Laubenstein, M. Marmor, B. Safai, S. Dritz, S. Crispi, S. Fannin, J. P. Orkwis, A. Kelter, W. R. Rushing, S. Thacker, J. Curran   +23 more
semanticscholar   +1 more source

Identification of Orthosteric and Allosteric Pharmacological Chaperones for Mucopolysaccharidosis Type IIIB

ChemBioChem, Volume 25, Issue 15, August 1, 2024.
We modeled substrate interactions in NAGLU′s active site and predicted allosteric sites. Virtual screening against a human‐tested molecule database identified potential pharmacological chaperones (PCs). In vitro evaluations confirmed their binding to NAGLU and ability to restore enzymatic activity in MPS IIIB fibroblasts with mutant enzymes.
Juan Camilo Losada, Heidy Triana, Egdda Vanegas, Angela Caro, Alexander Rodríguez‐López, Angela Johana Espejo‐Mojica, Carlos Javier Alméciga‐Diaz   +6 more
wiley   +1 more source

Fatal Case Due to Methicillin-Resistant Staphylococcus aureus Small Colony Variants in an AIDS Patient

Emerging Infectious Diseases, 1999
We describe the first known case of a fatal infection with small colony variants of methicillin-resistant Staphylococcus aureus in a patient with AIDS.
Harald Seifert, Christoph von Eiff, Gerd Fätkenheuer   +2 more
doaj   +1 more source

Evaluating the Efficacy of a Polymerase Chain Reaction Assay for Pneumocystis carinii Detection in Respiratory Samples

Journal of Medical Evidence
Introduction: Accurately identifying patients with pneumocystis pneumonia (PCP) presents considerable challenges, primarily relying on clinical suspicion.
Sonu Kumari Agarwal, Harendra Kumar Thakur, Bansidhar Tarai   +2 more
doaj   +1 more source

Biochemical research elucidating metabolic pathways in Pneumocystis*

Parasite, 2010
Advances in sequencing the Pneumocystis carinii genome have helped identify potential metabolic pathways operative in the organism. Also, data from characterizing the biochemical and physiological nature of these organisms now allow elucidation of ...
Kaneshiro E.S.
doaj   +1 more source

Newly formed cystic lesions for the development of pneumomediastinum in Pneumocystis jirovecii pneumonia

BMC Infectious Diseases, 2009
Background Pneumocystis jirovecii, formerly named Pneumocystis carinii, is one of the most common opportunistic infections in human immunodeficiency virus (HIV)-infected patients.
Yoon Sung, Kwon Yong, Kim Dong-Min, Cho Ju-Yeon, Lee Seung   +4 more
doaj   +1 more source

Bisbenzamidines as Antifungal Agents. Are Both Amidine Functions Required to Observe an Anti-Pneumocystis carinii Activity?

Molecules, 2010
A library of 19 novel 4-(4-phenylpiperazine-1-yl)benzamidines has been synthesized and evaluated in vitro against Pneumocystis carinii. Among these compounds, N-ethyl- and N-hexyl-4-(4-phenylpiperazine-1-yl)benzamidines emerged as the most promising ...
Julien Laurent, Dimitri Stanicki, Tien L. Huang, Eduardo Dei-Cas, Muriel Pottier, El Mouktar Aliouat, Jean Jacques Vanden Eynde   +6 more
doaj   +1 more source

Pneumocystis carinii Pneumonia (PCP)

Journal of Associated Medical Sciences, 2015
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Praijitr Tanan
doaj  

Co-evolution of the parasitic fungi Pneumocystis and their Muridae rodent hosts in Southeast Asia [PDF]

, 2014
Pneumocystis species are opportunistic and airborne-transmitted fungi that infect the lungs of numerous mammalian species. These highly diversified fungi are characterized by strong host specificity, probably associated with co-speciation. In this study,
Bezé, François, Chabé, Magali, Latinne, Alice, Morand, Serge   +3 more
core  

Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones [PDF]

, 2008
A series of primaquine-derived imidazolidin-4-ones were screened for their in vitro activity against Pneumocystis carinii and Plasmodium falciparum W2 strain. Most compounds were active against P.
Jiri Gut, Margaret S Collins, Melanie T Cushionc, Nuno Vale, Paula Gomes, Philip J Rosenthal, Ricardo Ferraz, Rui Moreira   +7 more
core   +1 more source