Results 71 to 80 of about 33,572 (257)

Neoadjuvant Four-Drug Combination Therapy for NSCLC With EGFR Mutation Avoiding Total Pneumonectomy

Frontiers in Oncology, 2020
We report a case of successful neoadjuvant four-drug combination therapy to avoid total pneumonectomy. A 33-year-old male patient was diagnosed with locally advanced non-squamous NSCLC harboring EGFR mutation in the left lower lobe.
Jingpei Li, Jingpei Li, Jingpei Li, Ke Xu, Ke Xu, Ke Xu, Weipeng Cai, Weipeng Cai, Weipeng Cai, Yalei Zhang, Yalei Zhang, Yalei Zhang, Xin Zeng, Fei Cui, Fei Cui, Fei Cui, Zhexue Hao, Zhexue Hao, Zhexue Hao, Jun Liu, Jun Liu, Jun Liu, Jianxing He, Jianxing He, Jianxing He   +24 more
doaj   +1 more source

Intraoperative bronchial stump air leak control by Progel® application after pulmonary lobectomy [PDF]

, 2015
Diffuse tracheobronchial calcification is a physiological condition associated with advanced age, especially in women. A calcified bronchus can be fractured during major lung resections (lobectomy, bilobectomy, and pneumonectomy), exposing patients to ...
Ibrahim, Mohsen, Menna, Cecilia, Pindozzi, Fioralba, Rendina, Erino A.   +3 more
core   +1 more source

Durable Response to Pazopanib (Tyrosine Kinase Inhibitor) in a Patient With EWSR1::CREM Gene Fusion Positive Intra‐Abdominal Unclassified Epithelioid Sarcoma

Genes, Chromosomes and Cancer, Volume 64, Issue 10, October 2025.
ABSTRACT EWSR1::CREM fusion positive intrabdominal sarcomas defines a rare emerging group of aggressive mesenchymal neoplasms with a predilection for the celomic cavity and often manifesting perplexing immunophenotypic profile. There is no specific standard of care therapeutic option though anecdotal reports response to pazopanib have been reported. We
Saba Shafi, Dan Jones, Xiaokang Pan, Marium Husain, Alan Rogers, Steve Oghumu, O. Hans Iwenofu   +6 more
wiley   +1 more source

Pneumonectomy in pulmonary metastasis [PDF]

Journal of Thoracic Disease, 2017
The risk of complication following pneumonectomy is high; therefore, the decision to perform pneumonectomy should be carefully evaluated. A retrospective multicenter study of patients with metastatic lung tumors who underwent pneumonectomy was conducted.The database from the Metastatic Lung Tumor Study Group of Japan was retrospectively reviewed ...
Yuichi Ozeki, Masafumi Kawamura, Norihiko Ikeda, Ichiro Yoshino, Sakae Okumura, Noriyuki Matsutani   +5 more
openaire   +3 more sources

Thoracotomies in Children in Low to Middle Income Countries: The Indications for Surgery

Pediatric Pulmonology, Volume 60, Issue 10, October 2025.
ABSTRACT Introduction There is a scarcity of data on the utilization of thoracotomy for lung pathology in children in low‐ and middle‐income countries (LMICs). These countries have high burdens of infectious diseases, especially tuberculosis, hydatic disease and Human immunodeficiency virus (HIV).
Jacobus Botha, Pierre Goussard, Jacques Janson, Zane Ismail, Jin Kim, Francois Retief, Jonathan Burke, André Gie, Delano Rhode, Pawel Schubert, Savvas Andronikou   +10 more
wiley   +1 more source

Epidural Analgesia Versus Systemic Opioids for Postoperative Pain Management After VATS: A Systematic Review and Meta‐Analysis

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 9, October 2025.
ABSTRACT Background Firm consensus on the best perioperative pain management after Video‐Assisted Thoracic Surgery (VATS) is lacking. Recommendations often assess different loco‐regional techniques as part of a multimodal approach, but few discuss omitting regional analgesia altogether, eliminating any risk of procedural complications.
Jimmy H. Holm, Mikkel Bak, Anne C. Brøchner   +2 more
wiley   +1 more source

Is Preoperative Anemia a Prognostic Marker in Patients Who Underwent Pneumonectomy for Non-Small Cell Lung Cancer?

Cerrahpaşa Medical Journal
Objective: Pneumonectomy is infrequently selected for lung resections due to the high rate of postoperative complications. Thus, identifying risk factors for complications and predicting potential prognostic factors in patients undergoing pneumonectomy ...
Burcu Kılıç, Gizem Özçıbık Işık , Tolunay Turan , Ezel Erşen , H. Volkan Kara, M. Kamil Kaynak , Akif Turna   +6 more
doaj   +1 more source

Expression of Heart Development Protein With EGF‐Like Domains 1 (HEG1) Decorated With Low‐Sulfated Keratan Sulfate in Human Malignant Pleural Mesothelioma

Pathology International, Volume 75, Issue 10, Page 504-512, October 2025.
The purpose of this study is to investigate sulfation modification of the glycan structure decorating HEG1, one of the diagnostic markers of malignant pleural mesothelioma (MPM), in MPM. Immunohistochemical analysis reveals low‐sulfated keratan sulfate (KS) expression, recognized by 294‐1B1 and R‐10G, in MPM tissues with HEG1 expression.
Koki Nakashima, Hitomi Hoshino, Zui Zhang, Tomoya O. Akama, Nobuyuki Kondo, Seiki Hasegawa, Yoshitaka Sekido, Mana Fukushima, Tamotsu Ishizuka, Motohiro Kobayashi   +9 more
wiley   +1 more source

Sarcopenia on preoperative chest computed tomography predicts cancer‐specific and all‐cause mortality following pneumonectomy for lung cancer: A multicenter analysis

Cancer Medicine, 2021
Background Mortality risk prediction in patients undergoing pneumonectomy for non‐small cell lung cancer (NSCLC) remains imperfect. Here, we aimed to assess whether sarcopenia on routine chest computed tomography (CT) independently predicts worse cancer ...
Fabian M. Troschel, Qianna Jin, Florian Eichhorn, Thomas Muley, Till D. Best, Konstantin S. Leppelmann, Chi‐Fu Jeffrey Yang, Amelie S. Troschel, Hauke Winter, Claus P. Heußel, Henning A. Gaissert, Florian J. Fintelmann   +11 more
doaj   +1 more source

Pleural Mesothelioma: Pathogenesis, Diagnosis, Treatment, Prognosis, and Survival

MedComm, Volume 6, Issue 9, September 2025.
This is an overview of current and emerging therapeutic strategies for pleural mesothelioma (PM), including chemotherapy, immunotherapy (ICIs, dendritic cell vaccines, CAR‐T therapy), anti‐angiogenic therapy, epigenetic modifications (DNA methylation, histone changes, non‐coding RNAs), and targeted therapy focusing on genomic alterations and signaling ...
Libo Zhang, Meijuan Huang
wiley   +1 more source