Results 161 to 170 of about 103,719 (282)

Resistance, heteroresistance, and fitness costs drive colistin treatment failure during <i>Acinetobacter baumannii</i> pneumonia. [PDF]

Proc Natl Acad Sci U S A
Hernandez-Bird J, He B, VanOtterloo LM, Billings EB, Huo W, Teodoro GIC, Echlin H, Rosch JM, Trent MS, Isberg RR.   +9 more
europepmc   +1 more source

Impact of Thoracic Duct Resection on Postoperative Body Composition Trajectory After Oesophagectomy: A Prospective Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Thoracic duct resection (TDR) is frequently performed during radical oesophagectomy to improve locoregional control in oesophageal squamous cell carcinoma (ESCC). However, its impact on postoperative body composition—particularly skeletal muscle mass—remains unclear.
Tae Hee Hong, Young Ho Yang, Ha Eun Kim, Byung Jo Park, Chang Young Lee, Jin Gu Lee, Dae Joon Kim   +6 more
wiley   +1 more source

Toxic interstitial lung disease in cattle. [PDF]

J Vet Diagn Invest
Barros CSL, Riet-Correa F, Mendes RE, Rissi DR.   +3 more
europepmc   +1 more source

Endothelium‐Treg Communication Through Extracellular Vesicle Transfer Exacerbates Acute Respiratory Distress Syndrome

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Here, we reveal that pulmonary endothelium‐derived EVs aggravate lung inflammation via destabilizing Tregs during ALI/ARDS. Mechanistically, Tregs absorbs EV‐Med1, which promotes the secretion of IL‐21. This cytokine in turn induces hyper‐phosphorylation of STAT3 in Tregs thus induing loss of Foxp3, creating an hyperinflammatory ALI/ARDS ...
Xu Liu, Wei Huang, Xiwen Zhang, Shiming Li, Haofei Wang, Zongsheng Wu, Shuangfeng Zi, Lu Wang, Ling Liu, Yi Yang, Jianfeng Xie, Mingzhu Zheng, Jie Chao, Haibo Qiu   +13 more
wiley   +1 more source

Antimicrobial peptide delivery to lung as peptibody mRNA in anti-inflammatory lipids treats multidrug-resistant bacterial pneumonia. [PDF]

Nat Biotechnol
Xue Y, Hou X, Wang S, Zhang Y, Zhong Y, Kang DD, Wang C, Li H, Yu C, Liu Z, Tian M, Cao D, Zheng YY, Deng B, Hamon P, Merad M, Dong Y.   +16 more
europepmc   +1 more source

Extracellular Vesicles Coordinate Bacterial Cloaking in Lung Epithelial Cells to Alleviate Acute Inflammatory Injury

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Schematic diagram of lung epithelial cell‐derived extracellular vesicles mediating bacterial cloaking to attenuate acute inflammatory injury. Lung epithelial cells attenuate early S. aureus infection by shedding extracellular vesicles that capture bacteria via surface receptors.
Feng Ding, Shengkai Gong, Haotian Luo, Dandan Wu, Xiaoshan Yang, Zihan Li, Dingmei Zhang, Peijie He, Jiani Liu, Lili Bao, Yang Zhou, Zhengyan Wang, Siying Liu, Pei Wang, Geng Dou, Shiyu Liu   +15 more
wiley   +1 more source

Staphylococcus aureus Extracellular Vesicles Enhance PslE‐Mediated Pathogenesis in Pseudomonas aeruginosa

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
PslE is essential for the ability of S. aureus‐derived extracellular vesicles to enhance P. aeruginosa pathogenicity. ABSTRACT Coinfection of Pseudomonas aeruginosa (P. aeruginosa) and Staphylococcus aureus (S. aureus) is frequently observed. Our previous study demonstrated that S. aureus‐derived extracellular vesicles (SaEVs) promote P.
Phawinee Subsomwong, Rojana Sukchawalit, Naoko Watabe, Akio Nakane, Krisana Asano   +4 more
wiley   +1 more source

Cell death-related gene signatures as dual-function biomarkers: Early diagnosis and therapeutic targeting in Staphylococcus aureus pneumonia. [PDF]

PLoS One
Qing C, Sun W, Yang C, Yao Y, Liang Q, Huang T, Lin L.   +6 more
europepmc   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Advances in Inhaled Nanoparticle Drug Delivery for Pulmonary Disease Management. [PDF]

FASEB J
Fan Y, Zhou Y, Zhao J, Zhao Y.
europepmc   +1 more source