Results 91 to 100 of about 374,956 (253)

A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage

Medical Mycology Case Reports, 2016
We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance.
Taylor Eddens, Eunkyung Song, Monica I. Ardura, Jay K. Kolls   +3 more
doaj   +1 more source

High prevalence of Pneumocystis jirovecii pneumonia among Mozambican children < 5 years of age admitted to hospital with clinical severe pneumonia [PDF]

, 2016
We aimed to describe Pneumocystis jirovecii pneumonia (PCP) prevalence and features in children from sub-Saharan Africa, and to investigate PCP-associated risk factors.
Acácio, Sozinho, Alonso, Pedro, Bassat Orellana, Quique, Calderon, Enrique J., Campano, E., Friaza, Vicente, Horra, C. de la, Lanaspa, Miguel, Machevo, Sonia, Madrid, Lola, Nhampossa, Tacilta, O'Callaghan Gordo, Cristina, Roca, A.   +12 more
core   +1 more source

Cohort Study to Determine the Impact of CYP3A5 Genotype on Tacrolimus Dosing Requirements and Trough Concentrations in Heart Transplant Recipients

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 3, March 2026.
ABSTRACT Background Tacrolimus is primarily metabolized by Cytochrome P450 (CYP)3A4/5. The Clinical Pharmacogenetics Implementation Consortium recommends increasing the initial dose 1.5‐ to 2‐fold in CYP3A5 expressers to enhance transplant outcomes. Our objective was to investigate the impact of CYP3A5 expresser status on tacrolimus dosing requirements
Yanting Wu, Michael T. Eadon, Laurie Schenkelberg, Roopa A. Rao, Todd C. Skaar, Emma M. Tillman, Tyler Shugg   +6 more
wiley   +1 more source

pneumonia in a healthy immunocompetent patient: A case report and literature review

SAGE Open Medical Case Reports
Pneumocystis jirovecii pneumonia, typically an opportunistic infection, is commonly associated with risk factors such as low CD4+ lymphocyte count, underlying malignancies, organ transplantation, or immunosuppressive medications.
Houda Rouis, Chirine Moussa, Yoldez Houcine, Ines Zendah, Hamida Kwas, Habib Ghedira, Sonia Maâlej   +6 more
doaj   +1 more source

Coexistência de infeções oportunistas pulmonares num doente com infeção por vírus da imunodeficiência humana e uma forma persistente de pneumonia por Pneumocystis jirovecii: caso clínico

Revista Portuguesa de Pneumologia, 2013
Resumo: Como é sabido, nos doentes com infeção por vírus da imunodeficiência humana (VIH) existe um alto risco de ocorrência de infeções oportunistas (IO), tais como as infeções por Pneumocystis jirovecii, um agente patogénico com distribuição mundial ...
D. Ponces Bento, F. Esteves, O. Matos, A.C. Miranda, F. Ventura, C. Araújo, K. Mansinho   +6 more
doaj   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Seasonal dynamics of Pneumocystis carinii in the field vole, Microtus agrestis, and in the common shrew, Sorex araneus, in Finland [PDF]

, 1999
Seasonal dynamics of Pneumocystis carinii in the field vole, Microtus agrestis, and in the common shrew, Sorex araneus, were investigated in southern and central Finland by microscopical examination of methenamine silver-stained tissue sections.
Henttonen, H., Laakkonen, J., Niemimaa, J., Soveri, T.   +3 more
core   +1 more source

A retrospective case series of 66 foals with presumed acute interstitial pneumonia

Equine Veterinary Education, Volume 38, Issue 3, Page 143-153, March 2026.
Summary Background There is limited literature describing acute interstitial pneumonia (AIP) in foals. Objectives Description of clinical and ultrasonographic findings in 66 foals affected by AIP. Investigation into whether the number of AIP cases is associated with specific climatic conditions. We also investigated whether clinical, haematological and
L. Weißlein, F. Freise, M. Venner
wiley   +1 more source

Risk Factors for Breakthrough Pneumocystis carinii Pneumonia on Aerosol Pentamidine Prophylaxis

Canadian Respiratory Journal, 1995
OBJECTIVE: To identify baseline characteristics of human immunodeficiency virus (HIV)-infected individuals on aerosol pentamidine for Pneumocystis carinii prophylaxis that are predictive of subsequent breakthrough Pneumocystis carinii pneumonia (PCP).
RA McIvor, AR Rachlis, P Berger, LR Lee Pack, Charles K Chan   +4 more
doaj   +1 more source

Serum markers in interstitial pneumonia with and without Pneumocystis jirovecii colonization: a prospective study

BMC Infectious Diseases, 2009
Background In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation.
Shimizu Yasuo, Sunaga Noriaki, Dobashi Kunio, Fueki Makoto, Fueki Naoto, Makino Sohei, Mori Masatomo   +6 more
doaj   +1 more source