Results 11 to 20 of about 374,956 (253)

Development and Evaluation of Rapid and Accurate CRISPR/Cas13-Based RNA Diagnostics for Pneumocystis jirovecii Pneumonia

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundPneumocystis jirovecii can result in a serious pulmonary infection, Pneumocystis jirovecii pneumonia, in immunocompetent hosts. The diagnosis of Pneumocystis jirovecii pneumonia has long been a major clinical concern, and there are limitations ...
Yangqing Zhan, Xiaoqing Gao, Shaoqiang Li, Yeqi Si, Yuanxiang Li, Xu Han, Wenjun Sun, Zhengtu Li, Feng Ye   +8 more
doaj   +2 more sources

Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG

Critical Care, 2023
Background Pneumocystis jirovecii pneumonia (PJP) is an opportunistic, life-threatening disease commonly affecting immunocompromised patients. The distribution of predisposing diseases or conditions in critically ill patients admitted to intensive care ...
D. Giacobbe, S. Dettori, V. di Pilato, E. Asperges, L. Ball, E. Berti, O. Blennow, B. Bruzzone, L. Calvet, Federico Capra Marzani, Antonio Casabella, Sofia Choudaly, Anais Dartevel, G. De Pascale, Gabriele Di Meco, Melissa Fallon, L. Galerneau, M. Gallego, M. Giacomini, Adolfo González Sáez, Luise Hänsel, G. Icardi, P. Koehler, K. Lagrou, T. Lahmer, P. Lewis White, L. Magnasco, A. Marchese, C. Marelli, M. Marín-Arriaza, I. Martín-Loeches, A. Mekontso-Dessap, M. Mikulska, A. Mularoni, A. Nordlander, J. Poissy, Giovanna Russelli, A. Signori, C. Tascini, Louis-Maxime Vaconsin, J. Vargas, A. Vena, J. Wauters, P. Pelosi, J. Timsit, M. Bassetti, Matteo Mario Chiara Denise Iole Filippo Sara Sofía Marice Cerchiaro Zaccarelli Robba Battaglini Brunetti Del, Matteo Cerchiaro, Mario Zaccarelli, C. Robba, D. Battaglini, I. Brunetti, F. Del Puente, Sara Mora, S. de la Villa, M. Valerio, Patricia Muñoz, G. Lombardi, Melania Cesarano, Veronica Gennenzi, P. Meersseman, G. Hermans, A. Wilmer, K. Razazi, G. Carteaux, N. de Prost, O. Cornely, D. Seidel, A. Alastruey‐Izquierdo, J. Garcia Borrega, C. Bonnal, E. de Montmollin, Julien Dessajan, M. Ceresini, F. Mojoli, A. Vola, C. Garnaud, E. Díaz, O. Gasch, E. Prina, S. Rasch, Miriam Dibos, Stefan Haschka   +82 more
semanticscholar   +1 more source

The Pathogenesis and Diagnosis of Pneumocystis jiroveci Pneumonia

Journal of Fungi, 2022
Pneumocystis jiroveci remains an important fungal pathogen in immunocompromised hosts. The environmental reservoir remains unknown. Pneumonia (PJP) results from airborne transmission, including in nosocomial clusters, or with reactivation after an ...
A. Apostolopoulou, J. Fishman
semanticscholar   +1 more source

Pneumocystis Pneumonia: Immunity, Vaccines, and Treatments

Pathogens, 2021
For individuals who are immunocompromised, the opportunistic fungal pathogen Pneumocystis jirovecii is capable of causing life-threatening pneumonia as the causative agent of Pneumocystis pneumonia (PCP). PCP remains an acquired immunodeficiency disease (
Aaron D. Gingerich, K. Norris, J. Mousa
semanticscholar   +1 more source

Diagnosing Pneumocystis jirovecii pneumonia: A review of current methods and novel approaches.

Medical Mycology, 2020
Pneumocystis jirovecii can cause life-threatening pneumonia in immunocompromised patients. Traditional diagnostic testing has relied on staining and direct visualization of the life-forms in bronchoalveolar lavage fluid.
M. Bateman, R. Oladele, J. Kolls
semanticscholar   +1 more source

Recent Advances in the Diagnosis and Management of Pneumocystis Pneumonia

Tuberculosis and Respiratory Diseases, 2020
In human immunodeficiency virus (HIV)-infected patients, Pneumocystis jirovecii pneumonia (PCP) is a wellk-nown opportunistic infection and its management has been established.
S. Tasaka
semanticscholar   +1 more source

Metagenomic Next-Generation Sequencing in Diagnosis of a Case of Pneumocystis jirovecii Pneumonia in a Kidney Transplant Recipient and Literature Review

Infection and Drug Resistance, 2020
Background Despite the increasing incidences of Pneumocystis jirovecii pneumonia (PCP) in renal transplant recipients, diagnosis of PCP remains challenging due to its nonspecific clinical presentation and the inadequate performance of conventional ...
Jie Chen, Ting He, Xiujun Li, Xue Wang, Li Peng, Liang Ma   +5 more
semanticscholar   +1 more source

Refractory flare-up of severe bronchial asthma controlled with mepolizumab due to Pneumocystis pneumonia: a case report

Allergy, Asthma & Clinical Immunology, 2022
Background Biologics dramatically improve symptoms of severe asthma; however, various exacerbating factors may induce flare-up. Pneumocystis spp. have not been reported as a cause of asthma exacerbation during biologic use, although patients with severe ...
Kazuya Takeda, Toshiyuki Sumi, Yuta Nagahisa, Keigo Matsuura, Motoki Sekikawa, Hiroki Watanabe, Yuichi Yamada, Hirofumi Chiba   +7 more
doaj   +1 more source

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. [PDF]

, 2019
IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe ...
Byanyima, Patrick, Chang, Emily G, Crothers, Kristina, Davis, J Lucian, Huang, Laurence, Hunt, Peter W, Kaswabuli, Sylvia, Lalitha, Rejani, Lederman, Michael M, Lin, Jue, Moisi, Daniela, Moore, Julia, Musisi, Emmanuel, Sanyu, Ingvar, Sessolo, Abdulwahab, Wang, Richard J, Worodria, William   +16 more
core   +2 more sources

Increased mortality in hematological malignancy patients with acute respiratory failure from undetermined etiology : a Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologique (Grrr-OH) study [PDF]

, 2016
Background: Acute respiratory failure (ARF) is the most frequent complication in patients with hematological malignancies and is associated with high morbidity and mortality.
Azoulay, Elie, Benoit, Dominique, Bruneel, Fabrice, Contejean, Adrien, Darmon, Michael, Hamidfar, Rebecca, Jourdain, Mercé, Kouatchet, Achille, Lemiale, Virginie, Mayaux, Julien, Meert, Anne-Pascale, Mokart, Djamel, Nyunga, Martine, Perez, Pierre, Pène, Frédéric, Rabbat, Antoine, Renault, Anne, Resche-Rigon, Matthieu, Schlemmer, Benoît, Vincent, François   +19 more
core   +2 more sources