Results 91 to 100 of about 89,681 (296)

Empiric Antimicrobial Therapy in Patients with Healthcare-Associated, Hospital-Acquired, or Ventilator-Associated Pneumonia in Septic Shock: Does Antimicrobial Reuse Influence Outcomes? [PDF]

open access: yes, 2017
Appropriate empiric antimicrobial selection is crucial to the survival of septic shock patients. It is suspected that the use of inadequate empiric therapy occurs commonly in practice.
Stagge, Nicole
core   +1 more source

Core components for effective infection prevention and control programmes: new WHO evidence-based recommendations [PDF]

open access: yes, 2017
Health care-associated infections (HAI) are a major public health problem with a significant impact on morbidity, mortality and quality of life. They represent also an important economic burden to health systems worldwide.
A Higgins   +113 more
core   +6 more sources

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

open access: yesiMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang   +13 more
wiley   +1 more source

Ventilator-associated pneumonia

open access: yesIntensive Care Medicine, 2022
Otavio T. Ranzani   +2 more
openaire   +3 more sources

Oral condition of critical patients and its correlation with ventilator-associated pneumonia: a pilot study

open access: yesRevista de Odontologia da UNESP
INTRODUCTION: Literature has reported inadequate oral hygiene conditions in Intensive Care Unit (ICU) patients and the occurrence of Ventilator-associated pneumonia in about 9%-27% of all intubated patients.
Andrea Carvalho De Marco   +5 more
doaj  

The importance of Clinical Research [PDF]

open access: yesHorizonte Médico, 2016
Objetives: to describe the clinical and epidemiological characteristics, evolution and to identify mortality factors associated in patients with snp.Material and methods: descriptive study of a serie of cases of the intensive care unit (icu) of a general
Frank Lizaraso Caparó   +1 more
doaj  

Ventilator-associated respiratory infection in a resource-restricted setting: impact and etiology

open access: yesJournal of Intensive Care, 2017
Background Ventilator-associated respiratory infection (VARI) is a significant problem in resource-restricted intensive care units (ICUs), but differences in casemix and etiology means VARI in resource-restricted ICUs may be different from that found in ...
Vu Dinh Phu   +29 more
doaj   +1 more source

Clinical and in vitro efficacy of colistin plus vancomycin and rifampin against colistin-resistant Acinetobacter baumannii causing ventilator-associated pneumonia [PDF]

open access: yes, 2017
We present the case of a patient with ventilator-associated pneumonia (VAP) caused by a pan-resistant Acinetobacter baumannii successfully treated with the combination colistin plus vancomycin plus rifampin, whose in vitro activity was investigated by ...
Cipolla, Alessia   +5 more
core   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

open access: yesInterdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang   +10 more
wiley   +1 more source

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