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Ventilator-Associated Pneumonia: A Review

Hospital Practice, 2012
Ventilator-associated pneumonia (VAP) is the most common infection seen in intensive care units (ICUs); it accounts for one-fourth of the infections occurring in critically ill patients and is the reason for half of antibiotic prescriptions in mechanically ventilated patients.
Madiha, Ashraf, Luis, Ostrosky-Zeichner
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Markers of ventilator-associated pneumonia

Clinical Intensive Care, 1995
The diagnosis of ventilator-associated pneumonia (VAP) is difficult for several reasons. Firstly, clinical markers show a large percentage of false-positive and false-negative results. Secondly, microbiological diagnosis based on quantitative cultures of protected specimen brush (PSB), bronchoalveolar lavage (BAL), and endotracheal aspirates also ...
M, el-Ebiary   +3 more
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The Prevention of Ventilator-Associated Pneumonia

Survey of Anesthesiology, 1999
Nosocomial pneumonia is a leading cause of death from hospital-acquired infections, with an associated crude mortality rate of approximately 30 percent.1 Ventilator-associated pneumonia refers specifically to nosocomial bacterial pneumonia that has developed in patients who are receiving mechanical ventilation.
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Diagnosis of ventilator-associated pneumonia

Journal of Critical Care, 2009
Ventilator-associated pneumonia (VAP) is difficult to diagnose. Recent data suggest quantitative endotracheal aspirate (ETA) may be noninferior diagnostically to quantitative bronchoalveolar lavage (BAL). We hypothesized this would be the case.Blind quantitative ETA and BAL were performed on 150 consecutive ventilated patients with suspected VAP in a ...
Medford, ARL   +3 more
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Diagnosing Ventilator-Associated Pneumonia

New England Journal of Medicine, 2004
The establishment of an appropriate diagnosis of ventilator-associated pneumonia is one of the most crucial and difficult issues in the care of critically ill patients. Established clinical criteria alone, such as new or progressive infiltrates on chest radiography, together with fever, leukocytosis or leukopenia, and purulent tracheobronchial ...
Antoni, Torres, Santiago, Ewig
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Update in ventilator-associated pneumonia

Current Opinion in Anaesthesiology, 2006
Ventilator-associated pneumonia remains an important topic (or subject) in the care of the critically ill. Issues related to ventilator-associated pneumonia are now particularly acute given the continued increase in rates of antimicrobial resistance seen in intensive care units.
William L, Jackson, Andrew F, Shorr
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Diagnosis of ventilator-associated pneumonia

Journal of Hospital Infection, 1999
The diagnosis of ventilator-associated pneumonia (VAP) is problematic despite numerous attempts at defining acceptable diagnostic criteria and the optimal technique for routine respiratory sampling. Clinical criteria have imperfect diagnostic reliability in ventilated patients, but remain crucial for defining those patients who may require respiratory ...
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Diagnosis of ventilator-associated pneumonia

Microbes and Infection, 2003
The diagnosis of ventilator pneumonia remains a controversial area. Use of standard clinical criteria has been found to be inadequate. Use of a clinical pulmonary infection score (CPIS) has improved the diagnostic utility of clinical criteria. For the intubated patient, there is ready access to the lower respiratory tract.
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Etiology of Ventilator-Associated Pneumonia

Clinics in Chest Medicine, 2005
This review focuses on the top ten causes of ventilator-associated pneumonia (VAP), updating an earlier study. These pathogens have specific risk factors, different patterns of clinical resolution, and a wide range of attributable mortality. The discussion herein analyzes these aspects, placing particular emphasis on risk factors, attributable ...
Jordi, Rello   +2 more
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Ventilator-associated pneumonia: an overview

Expert Opinion on Pharmacotherapy, 2009
Despite aggressive efforts to reduce nosocomial infections, many intubated patients develop ventilator-associated pneumonia (VAP). VAP has been an area of intense research; however, there is still little consensus in the literature on how to accurately diagnose or treat VAP.
Jennifer M, DiCocco, Martin A, Croce
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