Results 61 to 70 of about 54,423 (261)
Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
The effectiveness of a bundle in the prevention of ventilator-associated pneumonia
Brazilian Journal of Infectious Diseases, 2016 Objectives: The aim of this study was to evaluate the impact of a bundle called FAST HUG in ventilator-associated pneumonia, weigh the healthcare costs of ventilator-associated pneumonia patients in the intensive care unit, and hospital mortality due to ...
Cléria Rodrigues Ferreira +6 more
doaj +1 more source
Biomarkers of lung congestion and injury in acute heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
wiley +1 more source
SAGE Open MedicineIntroduction: To decrease the risk of complications from ventilator-associated pneumonia, it is essential to implement preventative measures in all ICU patients.
Hoan Minh Hoang +13 more
doaj +1 more source
Epidemiology of Ventilator-Associated Pneumonia
Chest, 2000 In summary, the method of diagnosis used for VAP accounts for reported differences in etiology, pathogenesis, and outcomes. Further studies are needed to assess outcomes related to various diagnostic methods rather than to assess the sensitivity and specificity of these methods.
openaire +2 more sources
Bacteremia in horses undergoing routine dental prophylaxis: Before, during, and after the procedure
Equine Veterinary Journal, EarlyView.Abstract Background Transient bacteremia after dental procedures is well‐documented in the literature, but the prevalence and clinical significance in horses remains largely unexplored. Objectives To assess whether routine dental prophylaxis in clinically healthy horses is associated with detection of bacteria in blood, using culture and 16S rDNA ...
Allison Dockery +3 more
wiley +1 more source
New Medical Schools, Access to Physicians, and Health Outcomes: Evidence From Japan
Health Economics, EarlyView.ABSTRACT We analyse the impact of the construction of medical schools and associated university hospitals in Japan during the 1970s, which was primarily driven by ‘One Prefecture, One Medical School Policy’ (OPOMS). We find that the number of physicians increased significantly in prefectures where a medical school was built, and this effect persisted ...
Kisho Hoshi
wiley +1 more source
Frequency of Ventilator-associated Pneumonia With 3-day Versus 7-day Ventilator Circuit Changes
Pediatrics and Neonatology, 2010 Ventilator-associated pneumonia (VAP) is a common clinical problem. Previous studies involving adult patient cohorts have assessed various risk factors associated with VAP, including ventilator circuit changes.
Ting-Chang Hsieh +5 more
doaj +1 more source
Methicillin-Resistant Staphylococcus aureus Hospital-Acquired Pneumonia/Ventilator-Associated Pneumonia. [PDF]
Semin Respir Crit Care Med, 2022 Pickens CI, Wunderink RG.
europepmc +1 more source
International Journal of Cancer, EarlyView.Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko +31 more
wiley +1 more source