Results 101 to 110 of about 1,362,134 (339)

Building HMM and molecular docking analysis for the sensitive detection of anti-viral pneumonia antimicrobial peptides (AMPs)

open access: yesScientific Reports, 2021
Pneumonia is the main reason for mortality among children under five years, causing 1.6 million deaths every year; late research has exhibited that mortality is increasing in the elderly.
Olalekan Olanrewaju Bakare   +2 more
doaj   +1 more source

Severe respiratory viral infection induces procalcitonin in the absence of bacterial pneumonia

open access: yesThorax, 2020
Introduction Procalcitonin expression is thought to be stimulated by bacteria and suppressed by viruses via interferon signalling. Consequently, during respiratory viral illness, clinicians often interpret elevated procalcitonin as evidence of bacterial ...
S. Gautam   +11 more
semanticscholar   +1 more source

Multivariate Contrastive Predictive Coding with Sliding Windows for Disease Prediction from Electronic Health Records

open access: yesAdvanced Intelligent Systems, EarlyView.
Adaptive multi‐indicator contrastive predictive coding is introduced as a self‐supervised pretraining framework for multivariate EHR time series. An adaptive sliding‐window algorithm and 2D convolutional neural network encoder capture localized temporal patterns and global indicator dependencies, enabling label‐efficient disease prediction that ...
Hongxu Yuan   +3 more
wiley   +1 more source

Integrating bioinformatics with network pharmacology and experimental validation analysis to reveal the pharmacological mechanism of Ma-xing-shi-gan-tang in treating viral pneumonia

open access: yesPhytomedicine Plus
Viral pneumonia is mainly caused by lung inflammation caused by viral infection, and respiratory syncytial virus pneumonia and adenovirus pneumonia are commonly seen in clinical practice.
Li Huie   +8 more
doaj   +1 more source

Bronchiolitis obliterans. [PDF]

open access: yes, 1989
Bronchiolitis obliterans in the adult patient is a relatively uncommon and vexing clinical entity. This confusion results because this pathologic finding occurs in a variety of diverse clinical settings.
King, TE
core  

Development of Mucoadhesive Gel Microbicide to Target Mucosal HIV Reservoirs [PDF]

open access: yes, 2014
The wide use of microbicide is mainly depends on its effectiveness, less frequent application, ready availability and most importantly cost. The aim of this work was to develop affordable microbicide mucoadhesive gel formulation of synthetic anti HIV ...
Shegokar, Ranjita, Singh, Kamalinder K
core   +1 more source

Role of Traditional Chinese Medicine in the Management of Viral Pneumonia

open access: yesFrontiers in Pharmacology, 2020
Viral pneumonia is one kind of acute respiratory tract infection caused by the virus. There have been many outbreaks of viral pneumonia with high contagiousness and mortality both in China and abroad, such as the great influenza in 1918, the severe acute
Shengyan Xi   +6 more
semanticscholar   +1 more source

Proteomic Analysis of Golden Sputum Reveals Pulmonary Complement Activation During Acute Chest Syndrome in Children With Sickle Cell Disease

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Acute chest syndrome (ACS) is one of the most common severe complications of sickle cell disease (SCD). In recent years, a major role of inflammation and innate immunity has been evidenced, but ACS pathophysiology remains incompletely understood, and therapeutic options are limited.
Slimane Allali   +14 more
wiley   +1 more source

Accuracy of the diagnosis of pneumonia in Canadian pediatric emergency departments: A prospective cohort study.

open access: yesPLoS ONE
BackgroundThe diagnosis of pediatric pneumonia and determination of the likely pathogen are complicated as the clinical picture overlaps with other respiratory illnesses, interpretation of radiographs is subjective, and laboratory results are rarely ...
Joan L Robinson   +17 more
doaj   +1 more source

Differential redox state contributes to sex disparities in the response to influenza virus infection in male and female mice [PDF]

open access: yes, 2018
Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple host factors, including age, sex, metabolic ...
Ann Maria Clemente   +17 more
core   +2 more sources

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