The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
wiley +1 more source
Retrospective Review of Fluoroscopic Swallowing Studies and Outcomes at an Academic Health Center [PDF]
, 2020 Introduction: Aspiration is often associated with underlying medical conditions and can cause pneumonia or death. Aspiration risk can be assessed via video fluoroscopic swallowing study (VFSS) or barium swallow (BaSw).
Kane, MD, Gregory C. +3 more
core +2 more sources
Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis. [PDF]
, 2020 BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) are at risk of exacerbations and pneumonia; how the risk factors interact is unclear.
A Anzueto +42 more
core +2 more sources
An ensemble-based approach by fine-tuning the deep transfer learning models to classify pneumonia from chest X-ray images [PDF]
SciTePress 2021, 2020 Pneumonia is caused by viruses, bacteria, or fungi that infect the lungs, which, if not diagnosed, can be fatal and lead to respiratory failure. More than 250,000 individuals in the United States, mainly adults, are diagnosed with pneumonia each year, and 50,000 die from the disease.
arxiv +1 more source
Pneumonia and Streptococcus pneumoniae vaccine [PDF]
Archives of Pharmacal Research, 2017 Pneumonia is an inflammatory disease of the lung, responsible for high morbidity and mortality worldwide. It is caused by bacteria, viruses, fungi, or other microorganisms. Streptococcus pneumoniae, a gram-positive bacterium with over 90 serotypes, is the most common causative agent.
Dong-Kwon Rhee +2 more
openaire +2 more sources
Automatic classification between COVID-19 pneumonia, non-COVID-19 pneumonia, and the healthy on chest X-ray image: combination of data augmentation methods [PDF]
Sci Rep 10, 17532 (2020), 2020 Purpose: This study aimed to develop and validate computer-aided diagnosis (CXDx) system for classification between COVID-19 pneumonia, non-COVID-19 pneumonia, and the healthy on chest X-ray (CXR) images. Materials and Methods: From two public datasets, 1248 CXR images were obtained, which included 215, 533, and 500 CXR images of COVID-19 pneumonia ...
arxiv +1 more source
Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]
, 2020 We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM +10 more
core +3 more sources
Malawian children with fast-breathing pneumonia with and without comorbidities
Pneumonia, 2021 Background Due to high risk of mortality, children with comorbidities are typically excluded from trials evaluating pneumonia treatment. Understanding heterogeneity of outcomes among children with pneumonia and comorbidities is critical to ensuring ...
Amy Sarah Ginsburg +9 more
doaj +1 more source
Klebsiella pneumoniae pneumonia
Heart & Lung, 1997 Klebsiella pneumoniae is an uncommon cause of community-acquired pneumonia except in alcoholics. Klebsiella may mimic pulmonary reactivation tuberculosis because it presents with hemoptysis and cavitating lesions. Klebsiella pneumoniae is a difficult infection to treat because of the organism's thick capsule.
Natalie C. Klein +7 more
openaire +3 more sources