Lamellarin D Acts as an Inhibitor of Type I Collagen Production
COL1A2 gene, encoding type I collagen, is a key target for pulmonary fibrosis. We established a screening system to identify small molecules that inhibit COL1A2 gene expression. Using this system, we screen a library of compounds and identify lamellarin D as a potent inhibitor of COL1A2 expression, suggesting lamellarin D is a promising new lung ...
Daisuke Okuno+19 more
wiley +1 more source
The effect of air pollution on morbidity and mortality among children aged under five in sub-Saharan Africa: Systematic review and meta-analysis. [PDF]
Lake EA, Karras J, Marks GB, Cowie CT.
europepmc +1 more source
From Medication to Complication: A Case Report of Acute Eosinophilic Pneumonia Associated With Naltrexone. [PDF]
Davoodi A+4 more
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Abstract A reduced proportion of peripheral class‐switched memory B cells (CSM‐B cells) is presumed to indicate ineffective germinal activity. The extent that this finding corresponds to a plausible germinal center failure pathophysiology in patients not diagnosed with CVID or hyper IgM syndrome is not known.
Vijaya Knight+3 more
wiley +1 more source
A systematic review and meta-analysis of phase III randomized controlled trials to assess the risk of pneumonia, URTIs, and VTE in multiple myeloma patients treated with isatuximab. [PDF]
Jones DT+10 more
europepmc +1 more source
ABSTRACT Anticipating the evolution of septic patients with community‐acquired pneumonia (CAP) is challenging for front‐line physicians in the Emergency Department (ED). Prognosis depends mainly on early identification, antibiotics, organ support, but also immune status.
Thomas Lafon+4 more
wiley +1 more source
ABSTRACT Lung adenocarcinoma is a common malignancy that can metastasize. The lung is also a common site for metastasis from other sites. Prompt and accurate diagnosis is critical for patient management. The diagnosis of lung adenocarcinoma can be occasionally challenging due to overlapping clinical and pathological features with adenocarcinomas from ...
Robert Pei+2 more
wiley +1 more source
Corrigendum to "Experience in the diagnosis and treatment of pneumonia caused by infection with Tropheryma whipplei: A case series" [Heliyon Volume 9, Issue 6, June 2023, Article e17132]. [PDF]
Fang Z+10 more
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Premature Mortality in Patients With Anorexia Nervosa: A Matched Cohort Study of Cause of Death
ABSTRACT Objective To determine the extent to which anorexia nervosa is associated with premature mortality. Method We carried out a matched cohort study of 7332 male and female patients with anorexia nervosa and 73,215 patient controls who were admitted between 1989 and 2023 in hospital centers of Quebec, Canada. We tracked the patients longitudinally
Nathalie Auger+7 more
wiley +1 more source
Pneumonia: Recent Updates on Diagnosis and Treatment. [PDF]
Khan MA, Bajwa A, Hussain ST.
europepmc +1 more source