Results 71 to 80 of about 1,621,058 (392)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Clinical features and prognosis of severe legionnaires’ disease requiring intensive care unit admission: a multicentric retrospective cohort study

Pneumonia
Introduction Legionella is the second cause of community-acquired pneumonia in Intensive Care Unit (ICU) patients. The aim of this study was to describe the epidemiology and outcome in patients with Legionella pneumonia (LP) in French ICUs.
Anaïs Dartevel, Louis-Marie Galerneau, Vincent Peigne, Nicholas Sedillot, Stephan Ehrmann, Alexandre Lautrette, Kada Klouche, Julien Poissy, Guillaume Thiery, Bertrand Sauneuf, Jean-Philippe Rigaud, Michel Ramakers, Cédric Daubin, Carole Schwebel, Nicolas Terzi   +14 more
doaj   +1 more source

Malawian children with fast-breathing pneumonia with and without comorbidities

Pneumonia, 2021
Background Due to high risk of mortality, children with comorbidities are typically excluded from trials evaluating pneumonia treatment. Understanding heterogeneity of outcomes among children with pneumonia and comorbidities is critical to ensuring ...
Amy Sarah Ginsburg, Tisungane Mvalo, Jun Hwang, Melda Phiri, Eric D. McCollum, Madalitso Maliwichi, Robert Schmicker, Ajib Phiri, Norman Lufesi, Susanne May   +9 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Respiratory dysbiosis as prognostic biomarker of disease severity for adults with community-acquired pneumonia requiring mechanical ventilation

Pneumonia
Objetives To ascertain the role of the lung microbiome in the development of severe pneumonia and its potential as a biomarker for disease progression. Methods BAL samples from 34 adults with severe community-acquired pneumonia (CAP) (17 viral, 8 viral ...
Loreto Vidaur, Amalur Guridi, Oihana Leizaola, Jokin Marin, Jordi Rello, Cristina Sarasqueta, Ane Sorarrain, Jose María Marimón   +7 more
doaj   +1 more source

Ventilator-associated pneumonia in adults: a narrative review

Intensive Care Medicine, 2020
Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections. Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic criteria. VAP is associated with prolonged duration of mechanical ventilation
L. Papazian, M. Klompas, C. Luyt
semanticscholar   +1 more source

Physical exercise and cardiac death due to pneumonia in male teenagers [Iznenadna smrt zbog upalće pluća za vrijeme tjelovježbe u trojice mladića] [PDF]

, 2009
From 1998 to 2008 we noticed 3 cardiac deaths in male teenagers aged 18-19 during or after physical exercise. The first was working at the site recreatively, the second was engaged in soccer recreatively and the third was professional soccer player.
Duraković, Lejla, Duraković, Zijad, Mišigoj Duraković, Marjeta, Škavić, Josip   +3 more
core  

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Efficacy and safety of IL-6 inhibitors in patients with COVID-19 pneumonia: a systematic review and meta-analysis of multicentre, randomized trials [PDF]

, 2021
Alessandro Belletti, Corrado Campochiaro, Marilena Marmiere, В. В. Лихванцев, Andrey Yavorovskiy, Lorenzo Dagna, Giovanni Landoni, Alberto Zangrillo, Ludhmila Abrahão Hajjar   +8 more
openalex   +1 more source

Pneumonia lipóide

Revista Portuguesa de Pneumologia, 2008
Dentre as afecções pulmonares exógenas, a pneumonia lipóide (PL), causada pela broncoaspiração de lipídeos, é uma doença pouco diagnosticada. Ela resulta da reacção tipo corpo estranho que se segue à presença de material lipídico dentro do parênquima pulmonar. Em geral, o agente etiológico é o óleo mineral utilizado como agente laxativo.
Gunther Kissmann, Mauro Zamboni, Andreia Salarini Monteiro, Aureliano M Cavalcanti de Sousa, Marilene Nascimento, Mauro Esteves, Paulo de Biasi, Deborah Cordeiro Lannes   +7 more
openaire   +2 more sources