Results 71 to 80 of about 4,470 (211)

Synthesis and in vitro evaluation of thermosensitive hydrogel scaffolds based on (PNIPAAm-PCL-PEG-PCL-PNIPAAm)/Gelatin and (PCL-PEG-PCL)/Gelatin for use in cartilage tissue engineering

, 2018
Background: Biodegradable thermosensitive hydrogel scaffolds based on novel three-block PCL-PEG-PCL and penta block PNIPAAm-PCL-PEG-PCL-PNIPAAm copolymers blended with gelatin were prepared and examined on functional behavior of chondrocytes. Methods: In
Roya Salehi (4910845), Azadeh Montaseri (337491), Ali Ramazani (556889), Soodabeh Davaran (843099), Reza Rahbarghazi (4910842), Solmaz saghebasl (4910848)   +5 more
core   +1 more source

Thermosensitive Nanocables Prepared by Surface-Initiated Atom Transfer Radical Polymerization

Nanoscale Research Letters, 2008
Thermosensitive nanocables consisting of Au nanowire cores and poly(N-isopropylacrylamide) sheaths (denoted as Au/PNIPAAm) were synthesized by surface-initiated atom transfer radical polymerization (SI-ATRP).
Wei Qingshan, Zhou Wenbo, Ji Jian, Shen Jiacong   +3 more
doaj   +1 more source

Micro/Nanostructured Materials and Microfluidic Diagnostic Platforms Enable Multimodal Detection of Circulating Tumor Cells

Exploration, Volume 6, Issue 5, October 2026.
Engineered micro/nanomaterials enable high‐efficiency CTC capture, release, and multimodal molecular profiling. Integrated with AI‐driven analytics, these platforms decode tumor heterogeneity and metastatic dynamics, advancing real‐time monitoring and precision oncology through DNA, RNA, and protein cross‐scale data fusion.
Hao Li, Jiaojiao Sun, Kunguo Liu, Shijie Wang, Bowen Fu, Hong Zhu, Peng Cao, Xin Han   +7 more
wiley   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

MedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song, Epiphane K. Silli, Yazhen Xu, Huixia Lv, Ruoxian Song   +4 more
wiley   +1 more source

PNIPAAm-based biohybrid injectable hydrogel for cardiac tissue engineering

Acta Biomaterialia, 2016
Injectable biomaterials offer a non-invasive approach to deliver cells into the myocardial infarct region to maintain a high level of cell retention and viability and initiate the regeneration process. However, previously developed injectable matrices often suffer from low bioactivity or poor mechanical properties. To address this need, we introduced a
Ali Navaei, Danh Truong, John Heffernan, Josh Cutts, David Brafman, Rachael W. Sirianni, Brent Vernon, Mehdi Nikkhah   +7 more
openaire   +2 more sources

Controlled Release of Metformin Hydrogen Chloride from Stimuli-responsive Hydrogel based on Poly(N- Isopropylacrylamide)/Chitosan/Polyvinyl Alcohol Composite

International Journal of Technology, 2020
Hydrogels are ideal biomaterials owing to their unique network structure that facilitates considerable hydrophilicity and biocompatibility. At the same time, hydrogels also possess soft physical properties when combined with living tissue.
Dhena Ria Barleany, Claudia Vivi Ananta, Fistia Maulina, Agus Rochmat, Hafid Alwan, Erizal   +5 more
doaj   +1 more source

Temperature-responsive mixed-mode column for the modulation of multiple interactions

Scientific Reports, 2022
In this study, mixed-mode chromatography columns have been investigated using multiple analyte interactions. A mixed-mode chromatography column was developed using poly(N-isopropylacrylamide) (PNIPAAm) brush-modified silica beads and poly(3 ...
Kenichi Nagase, Kosuke Matsumoto, Hideko Kanazawa   +2 more
doaj   +1 more source

3D Hydrodynamic Flow Lithography

Advanced Functional Materials, Volume 36, Issue 74, 14 September 2026.
ABSTRACT Continuous‐ and stop‐flow lithography are widely used to fabricate multi‐dimensional microstructures whose cross‐sectional morphology is dictated by the flow profile of multiple co‐flowing streams. Here, we introduce three‐dimensional hydrodynamic flow lithography (3D HFL), a platform for programmable generation of multi‐layered flow profiles ...
Yiying Zou, Mehmet Akif Sahin, Muhammad Zia Ullah Khan, Muhammad Usman Akhtar, Daniel Stoecklein, Ghulam Destgeer   +5 more
wiley   +1 more source

Temperature-modulated separation of vascular cells using thermoresponsive-anionic block copolymer-modified glass

Regenerative Therapy
Introduction: Vascular tissue engineering is a key technology in the field of regenerative medicine. In tissue engineering, the separation of vascular cells without cell modification is required, as cell modifications affect the intrinsic properties of ...
Tadashi Hirotani, Kenichi Nagase
doaj   +1 more source

Morfologia de hidrogéis-ipn termo-sensíveis e ph-responsivos para aplicação como biomaterial na cultura de células Morphology of temperature-sensitive and ph-responsive ipn-hydrogels for application as biomaterial for cell growth

Polímeros, 2009
No presente trabalho, foram sintetizados hidrogéis com ambas as propriedades, termo-sensíveis e pH-responsivos, pela formação de redes de alginato de cálcio (alginato-Ca) dentro de redes de poli(N-Isopropil Acrilamida) (PNIPAAm), resultando em um sistema
Adley F. Rubira, Edvani C. Muniz, Marcos R. Guilherme, Alexandre T. Paulino, Elias B. Tambourgi   +4 more
doaj   +1 more source