Results 1 to 10 of about 14,536 (127)

A novel PNIPAM-Modified polyurethane/carboxymethyl cellulose photo-thermoresponsive hydrogel loaded with gemcitabine to suppress esophageal cancer cells via VEGF-mediated angiogenic pathway inhibition [PDF]

open access: yesJournal of Biological Engineering
This study reports the development of a thermoresponsive hydrogel composed of poly(N-isopropylacrylamide)-modified polyurethane (PNIPAM-PU) and carboxymethyl cellulose (CMC) for the controlled delivery of gemcitabine (GEM) in esophageal cancer treatment.
Shirong Wu   +6 more
doaj   +2 more sources

Development of a Curcumin-Loaded Hyaluronic Acid Nanogel Formulation Using Wet Granulation Method for Enhanced Dissolution and Stability [PDF]

open access: yesGels
Curcumin is widely recognized for its various pharmacological properties, including antioxidant, anti-inflammatory, and anti-tumor activities. Nevertheless, the development of curcumin as a therapeutic agent is impeded by its limited oral bioavailability,
Natkhanang Mookkie Boonpetcharat   +3 more
doaj   +2 more sources

Development and bioevaluation of controlled release 5-aminoisoquinoline nanocomposite: a synergistic anticancer activity against human colon cancer

open access: yesAIMS Biophysics, 2022
The current study presents a bimodal therapeutic platform for cancer treatment. Bimodal implies that the presented drug loaded core-shell structure is capable of elevating the tumor tissue temperature (hyperthermia) through the superparamagnetic iron ...
Alaa AL-Rahman Gamal   +3 more
doaj   +1 more source

Poly(N-Isopropylacrylamide) Based Electrically Conductive Hydrogels and Their Applications

open access: yesGels, 2022
Poly(N-isopropylacrylamide) (PNIPAM) based electrically conductive hydrogels (PNIPAM-ECHs) have been extensively studied in recent decades due to their thermal-responsive (leading to the volume change of hydrogels) and electrically conductive performance.
Zexing Deng   +8 more
doaj   +1 more source

Thermo- and pH-Responsive Behavior of Poly(N-isopropylacrylamide)-Block-Poly[(2-dimethylamino)ethyl Methacrylate]

open access: yesIndonesian Journal of Chemistry, 2023
The influence of poly(2-dimethylamino)ethyl methacrylate (PDMAEMA) block on the thermo- and pH-responsive behavior of poly(N-isopropyl acrylamide)-block-poly[(2-dimethylamino)ethyl methacrylate)] (PNIPAM-b-PDMAEMA) was studied.
Noverra Mardhatillah Nizardo   +2 more
doaj   +1 more source

Characterization of Ball-milled Poly(Nisopropylacrylamide) Nanogels

open access: yesCurrent Directions in Biomedical Engineering, 2022
Poly(N-isopropylacrylamide) (PNIPAM) hydrogels are one of the most commonly studied thermoresponsive biomaterials. In this work, we investigate ball milling as a method of producing PNIPAM nanogels and confirm that the temperature responsiveness is ...
Huling Jennifer   +4 more
doaj   +1 more source

Experimental study on the temperature-sensitive behavior of poly-n-isopropylacrylamide/graphene oxide composites and the flexible conductive cotton fabrics

open access: yesPolymer Testing, 2022
This work focused on the development and characterization of poly-n-isopropylacrylamide/graphene oxide composite (PNIPAM-GO) which was prepared by in situ free radical polymerization of n-isopropylacrylamide and graphene oxide (GO).
Jinhong Tan   +5 more
doaj   +1 more source

Preparation and Anti-Mold Properties of Nano-ZnO/Poly(N-isopropylacrylamide) Composite Hydrogels

open access: yesMolecules, 2020
The aim of this study was to overcome drawbacks of the inhomogeneous dispersion and facile agglomeration of nano-ZnO/poly(N-isopropylacrylamide) composite hydrogels (nano-ZnO/PNIPAm composite hydrogels) during synthesis and improve the anti-mold property
Jingjing Zhang   +7 more
doaj   +1 more source

Colloidal Probes of PNIPAM-Grafted SiO2 in Studying the Microrheology of Thermally Sensitive Microgel Suspensions

open access: yesAdvances in Polymer Technology, 2020
The complex rheology and the phase behavior of thermally sensitive poly(N-isopropylacrylamide) (PNIPAM) microgels have been investigated in both the swollen and collapsed states by using microrheology.
Jing Shang   +4 more
doaj   +1 more source

A new approach to thermal responsivity and hydrodynamics of poly(N-isopropylacrylamide) in aqueous solution: all-atom and mesoscopic simulations

open access: yesMaterials Research Express, 2021
In this study, the impact of chemical and physical characteristics of poly(N-isopropylacrylamide) (PNIPAm) in water on its thermoresponsive behavior and aggregation was investigated via all-atom and mesoscopic simulations.
Sajad Rasouli   +2 more
doaj   +1 more source

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